Santarpia R P, Pollock J J, Renner R P, Spiechowicz E
State University of New York, School of Dental Medicine, Stony Brook.
J Prosthet Dent. 1990 Apr;63(4):437-43. doi: 10.1016/0022-3913(90)90234-4.
A site-specific agar replica technique for detecting Candida albicans on the acrylic resin denture surface of denture stomatitis patients has been developed. The method is selective for C. albicans during a finite incubation period with a specific synthetic growth medium. C. albicans colonies can be geographically observed on the replica and their presence can be correlated with inflammatory lesions visible on the mucosa of the maxillary and mandibular residual ridges. In 12 denture stomatitis patients studied, a close clinical correlation of Newton type III patients was noted but this clinical correlation could not be observed in Newton type I and II patients. In general, the number of C. albicans colonies increased with the severity of the inflammation. The findings are discussed in light of lack of knowledge of the etiology of the stomatitis. The importance of the replica method is also discussed.
已开发出一种用于检测义齿性口炎患者丙烯酸树脂义齿表面白色念珠菌的位点特异性琼脂复制品技术。该方法在特定合成生长培养基的有限孵育期内对白色念珠菌具有选择性。可以在复制品上从空间上观察到白色念珠菌菌落，并且它们的存在可以与在上颌和下颌残余牙槽嵴黏膜上可见的炎性病变相关联。在研究的12例义齿性口炎患者中，观察到牛顿III型患者存在密切的临床相关性，但在牛顿I型和II型患者中未观察到这种临床相关性。一般来说，白色念珠菌菌落的数量随着炎症的严重程度而增加。鉴于对口炎病因的了解不足，对这些发现进行了讨论。还讨论了复制品方法的重要性。
