Lim Lik Thai, Ruzmetova Nargiz, Ballinger Susan H, Moorthy Ramana S
Tennent Institute of Ophthalmology, Gartnavel General Hospital, 1053 Great Western Road, Glasgow, G12 0YN, UK.
Int Ophthalmol. 2011 Aug;31(4):349-51. doi: 10.1007/s10792-011-9459-3. Epub 2011 Aug 14.
The purpose of this study is to report a case of disseminated histoplasmosis in a patient with uveitis, after treatment with infliximab. The method employed in this study is single case report. Infliximab can be useful in controlling idiopathic uveitis, but can give rise to disseminated histoplamosis, especially in patients living in geographic areas where histoplasmosis is endemic. Clinicians should be aware of the possibility of rapid onset histoplasmosis in patients receiving anti-tumor necrosis factor agents. In such cases, these agents should be immediately stopped, investigations performed, and appropriate treatment started.
本研究的目的是报告1例使用英夫利昔单抗治疗后发生葡萄膜炎并播散性组织胞浆菌病的病例。本研究采用的方法是单病例报告。英夫利昔单抗可有效控制特发性葡萄膜炎，但可引发播散性组织胞浆菌病，尤其是在组织胞浆菌病流行地区居住的患者中。临床医生应意识到接受抗肿瘤坏死因子药物治疗的患者可能迅速发生组织胞浆菌病。在这种情况下，应立即停用这些药物，进行检查，并开始适当治疗。
