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马龙氏经肛顺行灌肠术:阿姆斯特丹经验。

The Malone antegrade continence enema procedure: the Amsterdam experience.

机构信息

Pediatric Surgical Center of Amsterdam, Emma Children's Hospital / AMC, Academic Medical Center, Amsterdam 1105 AZ, The Netherlands.

出版信息

J Pediatr Surg. 2011 Aug;46(8):1603-8. doi: 10.1016/j.jpedsurg.2011.04.050.

Abstract

BACKGROUND

The Malone antegrade continence enema (MACE) procedure has been previously described as a safe and effective option for the treatment of children with chronic defecation disorders when maximal medical therapy and conventional treatment have failed.

PURPOSE

To evaluate clinical success, complications, and quality of life of children with chronic defecation disorders with a MACE stoma.

METHODS

A retrospective analysis of 23 patients who underwent the construction of a MACE stoma was performed. Preoperative and postoperative data were evaluated. A specific questionnaire was used to assess patient satisfaction.

RESULTS

A significant increase was found in defecation frequency (1.0 [range, 0-4] pretreatment vs 5.5 [range, 0-28] posttreatment per week; P < .006) and a significant decrease in fecal incontinence frequency (10 [range, 0-14] pretreatment vs 0 [range, 0-14] posttreatment per week; P < .034). Postoperative complications of the MACE procedure were fecal leakage (43%), wound infection (52%), and stomal stenosis (39%). A total of 86% of the patients were satisfied with the results of the Malone stoma (n = 21).

CONCLUSIONS

The MACE procedure is an effective treatment in children with intractable defecation disorders. Postoperative complications are, however, not uncommon. Further refinement of the technique focused to reduce the complication rate is necessary to expand the application of this approach.

摘要

背景

Malone 经肛顺行灌肠术(MACE)此前已被描述为一种安全有效的治疗方法,适用于最大程度药物治疗和常规治疗失败的慢性排便障碍患儿。

目的

评估 MACE 造口术治疗慢性排便障碍患儿的临床成功率、并发症和生活质量。

方法

对 23 例行 MACE 造口术的患者进行回顾性分析。评估了术前和术后的数据。使用特定问卷评估患者满意度。

结果

排便频率显著增加(1.0 [范围,0-4] 术前 vs 5.5 [范围,0-28] 术后每周;P <.006),粪便失禁频率显著降低(10 [范围,0-14] 术前 vs 0 [范围,0-14] 术后每周;P <.034)。MACE 手术后的并发症包括粪便渗漏(43%)、伤口感染(52%)和造口狭窄(39%)。86%的患者对 Malone 造口术的结果满意(n = 21)。

结论

MACE 手术是治疗难治性排便障碍患儿的有效方法。但术后并发症并不少见。需要进一步改进技术以降低并发症发生率,从而扩大该方法的应用。

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