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右半结肠切除术与左半结肠切除术治疗结肠癌的疗效比较。

Outcomes of right vs. left colectomy for colon cancer.

机构信息

Department of Surgery, University of California, Irvine Medical Center, Orange, CA 92868, USA.

出版信息

J Gastrointest Surg. 2011 Nov;15(11):2023-8. doi: 10.1007/s11605-011-1655-y. Epub 2011 Aug 16.

Abstract

BACKGROUND

Right colectomy (RC) is generally believed to be a simpler operation with better outcomes than left colectomy (LC). Our study was primarily intended to compare patient characteristics and perioperative outcomes between RC and LC in colon cancer patients, and secondarily to identify factors that increase the risk of developing postoperative abdominal abscess and/or anastomotic leak.

METHODS

Using the 2007 Nationwide Inpatient Sample database, we evaluated patients who underwent elective RC and LC for colon cancer.

RESULTS

A total of 50,799 patients underwent elective RC and LC for malignancy during 2007 (RC, 63.5%; LC, 36.5%). Overall, 9.6% were performed laparoscopically (RC, 9.7% vs. LC, 9.5%, P = 0.39). The majority of patients were Caucasian; 54.2% of RC and 46.5% LC patients were female (P < 0.01). RC patients were older (mean age, 70.8 vs. 65.8 years, P < 0.01) and had more comorbidities. While LC had more overall intraoperative complications (RC, 0.30% vs. LC, 1.32%, P < 0.01), RC had higher overall incidence of postoperative complications (28.43% vs. 26.75%, P < 0.01). Mean length of hospital stay (RC, 7.37 days vs. LC, 7.38 days) and in-hospital mortality (RC, 1.37% vs. LC, 1.49%) were similar in both groups. Multivariate analysis identified Native American race [adjusted odd ratio (AOR), 2.02], chronic renal failure (AOR, 1.97), congestive heart failure (AOR, 1.72), chronic pulmonary disease (AOR, 1.40), metastatic disease (AOR, 1.34), male gender (AOR, 1.23), and LC (AOR, 1.12) all independently increased the risk of abscess and/or leak.

CONCLUSIONS

RC patients were older and had more comorbidities and postoperative complications. Patient characteristics and comorbidities were more important in determining overall postoperative complications than anastomotic types.

摘要

背景

右半结肠切除术(RC)通常被认为比左半结肠切除术(LC)更简单,手术效果更好。本研究主要旨在比较结肠癌患者中 RC 和 LC 的患者特征和围手术期结果,并其次确定增加术后腹部脓肿和/或吻合口漏的风险因素。

方法

使用 2007 年全国住院患者样本数据库,我们评估了 2007 年接受择期 RC 和 LC 治疗结肠癌的患者。

结果

共有 50799 例患者接受择期 RC 和 LC 治疗恶性肿瘤(RC,63.5%;LC,36.5%)。总体而言,9.6%的患者行腹腔镜手术(RC,9.7% vs. LC,9.5%,P=0.39)。大多数患者为白种人;RC 患者中有 54.2%为女性,LC 患者中有 46.5%为女性(P<0.01)。RC 患者年龄较大(平均年龄,70.8 岁 vs. 65.8 岁,P<0.01)且合并症更多。虽然 LC 术中并发症总体发生率较高(RC,0.30% vs. LC,1.32%,P<0.01),但 RC 术后并发症总发生率较高(RC,28.43% vs. LC,26.75%,P<0.01)。两组的平均住院时间(RC,7.37 天 vs. LC,7.38 天)和住院死亡率(RC,1.37% vs. LC,1.49%)相似。多变量分析确定了美国原住民种族[校正比值比(AOR),2.02]、慢性肾衰竭(AOR,1.97)、充血性心力衰竭(AOR,1.72)、慢性肺部疾病(AOR,1.40)、转移性疾病(AOR,1.34)、男性(AOR,1.23)和 LC(AOR,1.12)均独立增加了脓肿和/或漏的风险。

结论

RC 患者年龄较大,合并症和术后并发症较多。患者特征和合并症比吻合类型更能决定总体术后并发症。

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