Schneider A W, Huland H
Urologische Universitätsklinik und Poliklinik, Hamburg-Eppendorf.
Urologe A. 1990 Mar;29(2):71-6.
Ideal tumor markers for use in the primary diagnosis or follow up of superficial or invasive cancers have not yet been found. Nonetheless, the literature contains references to parameters that are relevant to prognosis and to markers for bladder tumors, and many of these are certainly of value when specific questions are addressed. Urinalysis has been considerably refined and yields information on superficial tumors. Quantitative immunocytology is used to check whether prophylactic treatments are indicated and, if so, for how long; conventional cytology is helpful in the clinical follow up after BCG treatment of carcinoma in situ. In the present paper all important markers for urothelial cancer are reviewed and their value in diagnosis and treatment is discussed.
尚未找到可用于浅表性或浸润性癌症的初步诊断或随访的理想肿瘤标志物。尽管如此，文献中提到了一些与预后相关的参数以及膀胱肿瘤标志物，当涉及特定问题时，其中许多标志物肯定具有价值。尿液分析已得到相当大的改进，并能提供有关浅表肿瘤的信息。定量免疫细胞术用于检查是否需要进行预防性治疗，如果需要，治疗时长是多久；传统细胞学检查有助于原位癌卡介苗治疗后的临床随访。本文综述了尿路上皮癌的所有重要标志物，并讨论了它们在诊断和治疗中的价值。
