[适体：在病原微生物中的特性与应用]

[Aptamers: characteristics and applications in pathogenic microorganism].

作者信息

Liang Hongru, Yang Songtao, Zhang Tao, Hu Guiqiu, Xia Xianzhu

机构信息

College of Animal Science and Veterinary, Jilin University, Changchun 130062, China.

出版信息

Sheng Wu Gong Cheng Xue Bao. 2011 May;27(5):698-703.

PMID:21845835

Abstract

Aptamers are a group of artificial oligonucleotides identified by exponential enrichment system evolution technology (Selective expansion of ligands by exponential enrichment, SELEX). Aptamers have been widely used in basic research, clinical diagnostics, and nano-technology. In this article we will introduce the technology of aptamer and summarize its applications in medical microbiology.

摘要

适配体是通过指数富集系统进化技术（指数富集的配体系统进化技术，SELEX）鉴定出的一组人工寡核苷酸。适配体已广泛应用于基础研究、临床诊断和纳米技术领域。在本文中，我们将介绍适配体技术，并总结其在医学微生物学中的应用。