以色列住院儿童轮状病毒肠胃炎的特征

Characteristics of rotavirus gastroenteritis in hospitalized children in Israel.

作者信息

Perl Sivan, Goldman Michael, Berkovitch Matitiahu, Kozer Eran

机构信息

Pediatric Emergency Unit, Assaf Harofeh Medical Center, Zerifin, Israel.

出版信息

Isr Med Assoc J. 2011 May;13(5):274-7.

PMID:21845967

Abstract

BACKGROUND

Diarrhea is a leading cause of child mortality worldwide. Rotavirus is one of the most common causes of severe diarrhea and dehydration in children.

OBJECTIVES

To compare the demographic, clinical and laboratory characteristics of patients with rotavirus gastroenteritis to those with other causes of gastroenteritis.

METHODS

The medical records of children aged 0-18 years hospitalized with acute gastroenteritis in our facility between 1 January 2004 and 31 March 2006 were retrieved. Patients with rotavirus gastroenteritis were compared with patients who were rotavirus negative.

RESULTS

The study group comprised 533 patients; 202 tested positive for rotavirus and 331 tested negative. Compared to patients with rotavirus-negative gastroenteritis, patients with rotavirus-positive gastroenteritis had a higher incidence of vomiting (185/202 vs. 212/331, 92% vs. 64%, P < 0.001), lethargy (67/202 vs. 51/331, 33% vs. 15%, P < 0.001), and dehydration (81/202 vs. 78/331, 40% vs. 24%, P < 0.001). The need for intravenous rehydration therapy and the duration of hospitalization were higher in patients with rotavirus gastroenteritis.

CONCLUSIONS

Vomiting and dehydration are more common in hospitalized children with rotavirus gastroenteritis than in children with gastroenteritis due to other causes.

摘要

背景

腹泻是全球儿童死亡的主要原因之一。轮状病毒是儿童严重腹泻和脱水的最常见原因之一。

目的

比较轮状病毒性胃肠炎患者与其他原因引起的胃肠炎患者的人口统计学、临床和实验室特征。

方法

检索了2004年1月1日至2006年3月31日期间在我们机构因急性胃肠炎住院的0至18岁儿童的病历。将轮状病毒性胃肠炎患者与轮状病毒检测阴性的患者进行比较。

结果

研究组包括533名患者；202人轮状病毒检测呈阳性，331人检测呈阴性。与轮状病毒阴性的胃肠炎患者相比，轮状病毒阳性的胃肠炎患者呕吐发生率更高（185/202对212/331，92%对64%，P<0.001）、嗜睡发生率更高（67/202对51/331，33%对15%，P<0.001）和脱水发生率更高（81/202对78/331，40%对24%，P<0.001）。轮状病毒性胃肠炎患者需要静脉补液治疗的比例和住院时间更长。