[Methodology and assessment of testing bronchial reactivity].

Starting from diagnostic relevance of non specific bronchial challenges the principles and experiences of a screening type acetylcholine test which is recommended as a standard in GDR since 1974 are discussed. For special tasks like longitudinal studies and clinical pharmacology a threshold method using histamine was derived and modified from literature. Special attention is paid to diagnostic, prognostic and expertizing relevance of non specific bronchial hyperreactivity.