Department of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Rhode Island Hospital, 593 Eddy St, Providence, RI 02903, USA.
Radiology. 2011 Sep;260(3):633-55. doi: 10.1148/radiol.11091126.
Primary and secondary lung malignancies are often treated with surgery. Many patients are poor surgical candidates owing to advanced age or medical comorbidities. Alternatives to surgery for localized disease include radiation therapy and the newer treatments known as image-guided thermal ablation. Image-guided thermal ablation involves the use of needlelike applicators that are placed directly into tumors by using imaging guidance. Tumors are destroyed by the application of either intense heat or cold. The specific ablative modalities of radiofrequency ablation, microwave ablation, laser ablation, and cryoablation are reviewed with respect to the various clinical indications for treatment of both primary and secondary lung malignancies.
原发性和继发性肺部恶性肿瘤通常采用手术治疗。许多患者由于年龄较大或存在合并症而不适合手术。对于局限性疾病，手术的替代方法包括放射治疗和被称为影像引导热消融的新疗法。影像引导热消融涉及使用针状器械，通过影像引导直接将其放置到肿瘤中。通过施加高温或低温来破坏肿瘤。本文回顾了射频消融、微波消融、激光消融和冷冻消融等各种消融方式，讨论了其在原发性和继发性肺部恶性肿瘤治疗中的各种适应证。
