Breyer J, Jacobson H R
Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232.
Annu Rev Med. 1990;41:265-75. doi: 10.1146/annurev.me.41.020190.001405.
Recent identification of the renal epithelial cell ion transporters inhibited by diuretics allows physicians to select appropriate types and doses of diuretics. The desirable and undesirable clinical consequences of these molecular mechanisms of action can also be predicted.
近期对受利尿剂抑制的肾上皮细胞离子转运体的鉴定,使医生能够选择合适类型和剂量的利尿剂。这些分子作用机制所产生的有利和不利的临床后果也能够被预测。