Brozena S, Jessup M
Department of Cardiology, Heart Failure and Transplant Center, Temple University Hospital, Philadelphia, Pennsylvania 19140.
Annu Rev Med. 1990;41:65-74. doi: 10.1146/annurev.me.41.020190.000433.
The management of patients with congestive heart failure is based upon an understanding of the pathogenetic mechanisms. Therapy aimed at optimizing preload, decreasing afterload, and improving contractility can improve symptoms, and in some instances, improve survival.