Epilepsy Center, Children's Memorial Hospital, Chicago, IL 60614, USA.
Epilepsy Behav. 2011 Oct;22(2):336-41. doi: 10.1016/j.yebeh.2011.07.014. Epub 2011 Aug 17.
Epilepsy is associated with academic and neurocognitive disorders, with the latter often assumed to explain the former. We examined utilization of special education services (SpES) in relation to neurocognitive test scores in a case-matched sibling control study. In a follow-up assessment 8-9 years after entry into a prospective study of childhood-onset epilepsy, cases and siblings participated in an interview and standardized neurocognitive testing. Analyses included 142 pairs in which both had Full Scale IQ ≥ 80 and the case had normal examination and imaging. Sixty-four (45%) cases and 25 (17.6%) controls reported SpES utilization, (matched odds ratio [mOR]=5.3, P<0.0001). Adjustment for neurocognitive test scores resulted in a mOR of 4.6 (P<0.0001). Types and duration of services were similar in cases and controls. Twenty-four percent of school-aged cases were already receiving services at the time of initial epilepsy diagnosis. Young people with epilepsy have academic difficulties that are not explained simply by cognitive test scores.
癫痫与学业和神经认知障碍有关，后者通常被认为是前者的原因。我们在病例匹配的同胞对照研究中，检查了特殊教育服务（SpES）的利用情况与神经认知测试分数之间的关系。在进入儿童期起病的癫痫前瞻性研究后 8-9 年的随访评估中，病例和同胞接受了访谈和标准化神经认知测试。分析包括 142 对病例和同胞，他们的全量表智商均≥80，且病例的检查和影像学结果正常。64 名（45%）病例和 25 名（17.6%）对照报告了 SpES 的使用情况（匹配比值比 [mOR]=5.3，P<0.0001）。调整神经认知测试分数后，mOR 为 4.6（P<0.0001）。病例和对照组的服务类型和持续时间相似。在初始癫痫诊断时，24%的学龄期病例已经在接受服务。患有癫痫的年轻人存在学业困难，这些困难不能仅用认知测试分数来解释。
