Teagasc, Moorepark Dairy Production Research Centre, Fermoy, Co, Cork, Ireland.
Ir Vet J. 2009 Apr 1;62 Suppl 4(Suppl 4):265-71. doi: 10.1186/2046-0481-62-4-265.
The objective of this study was to investigate the impact of paratuberculosis sero-status on milk yield, fat, protein, somatic cell count and calving interval in Irish dairy herds. Serum from all animals over 12 months of age (n = 2,602) in 34 dairy herds was tested for antibodies to Mycobacterium avium subsp. paratuberculosis using an ELISA. Herds were categorised by sero-status into positive, non-negative and negative, where a positive herd contained two or more positive cows, a non-negative herd contained only one positive cow and a negative herd contained no positive cows. Data at animal, parity and herd-level were analysed by multiple regression using general linear models. Positive herds (mean herd size = 129 cows) and non-negative herds (81 cows) were larger than negative herds (72 cows) (P < 0.01). Negative herds had the highest economic breeding index (EBI), while positive herds had the highest estimated breeding value (EBV) for milk yield. There was no significant effect of paratuberculosis sero-status at animal, parity or herd-level on milk yield, milk fat or protein production, somatic cell count score (SCCS) or calving interval. Negative herds tended to have a lower SCCS than positive and nonnegative herds (P = 0.087). This study only examined the effects of paratuberculosis sero-status but did not examine the clinical effects of Johne's disease at the farm or dairy industry levels.
本研究旨在调查副结核病血清阳性状态对爱尔兰奶牛群产奶量、脂肪、蛋白质、体细胞计数和产犊间隔的影响。使用 ELISA 方法检测了 34 个奶牛场 12 月龄以上的所有动物（n=2602）的血清中的抗分枝杆菌副结核亚种的抗体。根据血清阳性状态将牛群分为阳性、非阴性和阴性，其中阳性牛群包含 2 头或更多阳性牛，非阴性牛群仅包含 1 头阳性牛，阴性牛群不包含阳性牛。通过使用一般线性模型的多元回归分析动物、胎次和牛群水平的数据。阳性牛群（平均牛群大小=129 头）和非阴性牛群（81 头）比阴性牛群（72 头）更大（P<0.01）。阴性牛群的经济育种指数（EBI）最高，而阳性牛群的产奶量的估计育种值（EBV）最高。副结核病血清阳性状态在动物、胎次或牛群水平上对产奶量、乳脂或蛋白质产量、体细胞计数评分（SCCS）或产犊间隔没有显著影响。阴性牛群的 SCCS 倾向于低于阳性和非阴性牛群（P=0.087）。本研究仅检查了副结核病血清阳性状态的影响，但未在农场或乳品行业水平上检查约翰氏病的临床影响。
