Department of Neuroradiology, University Medicine Goettingen, Germany.
AJNR Am J Neuroradiol. 2011 Nov-Dec;32(10):1956-62. doi: 10.3174/ajnr.A2611. Epub 2011 Aug 18.
Important findings, such as aneurysm remnants or major arterial occlusion, can be detected on intra- or postoperative angiography after surgical clipping of intracranial aneurysms. The purpose of this study was to evaluate the feasibility of IV-ACT for the postoperative detection of residual aneurysms and parent vessel patency compared with IA-DSA, which was selected as the standard reference method.
Twenty-two patients with 27 aneurysms treated by surgical clipping were examined by using both IA-DSA and IV-ACT. Both diagnostic procedures were performed on an FPD-equipped angiography system. Postprocessing of IV-ACT acquisitions was performed on a dedicated workstation producing multiplanar reformations and maximum intensity projections of the clip region and other intracranial arteries. Three interventional neuroradiologists independently evaluated both procedures.
A residual aneurysm was delineated in 10 cases with IA-DSA. Sufficient opacification of the intracranial vessels was assigned in 26 IV-ACT cases. Due to metal artifacts, IV-ACT images were tagged as "not diagnostic" on 8 occasions. In the other 19 aneurysms, a residual aneurysm was delineated in 6 cases-all 6 being true-positive compared with IA-DSA-and was excluded in the remaining 13 cases-all true-negative. Even small aneurysm remnants with a diameter of 1.5 mm were detected with IV-ACT.
Currently IV-ACT cannot be recommended as a routine tool for postoperative evaluation of clipped aneurysms due to metal artifacts in 30% of the examinations. These artifacts appear with multiple normal-sized or large clips. In patients with single or multiple small clips, IV-ACT can reliably show aneurysm remnants.
颅内动脉瘤夹闭术后,通过术中或术后血管造影术(intra-或 postoperative angiography)可以检测到重要发现,例如动脉瘤残余或主要动脉闭塞。本研究旨在评估 IV-ACT 检测术后残余动脉瘤和载瘤动脉通畅性的可行性,并与作为标准参考方法的数字减影血管造影术(digital subtraction angiography,DSA)进行比较。
对 22 例 27 个接受手术夹闭治疗的动脉瘤患者进行了数字减影血管造影术(IA-DSA)和 IV-ACT 检查。两种诊断程序均在配备 FPD 的血管造影系统上进行。IV-ACT 采集的后处理是在专用工作站上进行的,该工作站可生成夹闭区域和其他颅内动脉的多平面重建和最大强度投影。三位介入神经放射科医生独立评估了这两种程序。
IA-DSA 显示 10 例存在残余动脉瘤。26 例 IV-ACT 检查颅内血管充分显影。由于金属伪影,8 次 IV-ACT 图像被标记为“不可诊断”。在其他 19 个动脉瘤中,6 个动脉瘤(均与 IA-DSA 结果一致,为真阳性)显示出残余动脉瘤,而另外 13 个动脉瘤(均为真阴性)未显示出残余动脉瘤。即使是直径为 1.5mm 的小动脉瘤残余也可以通过 IV-ACT 检测到。
由于 30%的检查存在金属伪影,目前 IV-ACT 不能作为夹闭后动脉瘤术后评估的常规工具。这些伪影出现在多个正常大小或大的夹闭器中。在单个或多个小夹闭器的患者中,IV-ACT 可以可靠地显示动脉瘤残余。