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血管造影 C 臂 CT 可视化编织型 EndoBridge 颅内动脉瘤栓塞装置(WEB):动物模型中首项应用经验。

Angiographic C-arm CT visualization of the Woven EndoBridge cerebral aneurysm embolization device (WEB): first experience in an animal aneurysm model.

机构信息

Department of Neuroradiology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany,

出版信息

Clin Neuroradiol. 2014 Mar;24(1):43-9. doi: 10.1007/s00062-013-0224-z. Epub 2013 May 28.

DOI:10.1007/s00062-013-0224-z
PMID:23712863
Abstract

INTRODUCTION

Improvements in the imaging capabilities of angiographic C-arm computed tomography (CT) using flat detector angiographic (FD-CT) systems now provide a means for the in vivo visualization of devices used for the treatment of intracranial aneurysms. One such device, the WEB embolization device, is made of a braided mesh of nitinol wires, the size of which are near to the limits of visualization using conventional x-ray fluoroscopy. Our hypothesis was that the imaging of these implants C-arm CT would provide useful information regarding their positioning and deployment.

METHODS

In five New Zealand white rabbits elastase induced aneurysms were created and subsequently treated using a WEB. Imaging was performed using digital subtraction angiography (DSA), X-ray imaging and two different Angiographic C-arm CT protocols. The images were evaluated by two neuroradiologists using an evaluation scale.

RESULTS

The mesh of the WEB was barely visible on the DSA or x-ray fluoroscopy images. Volume rendering technique (VRT) reconstruction and multiplanar reconstruction (MPR) of images done using the C-arm CT protocols clearly delineated the shape and structure of the device. Contrast-enhanced MPR and VRT reconstructions allowed assessment of the status of blood flow in the aneurysms. Beam hardening artifacts caused by platinum markers on the WEB were present.

CONCLUSION

In vivo C-arm CT imaging of the WEB is feasible and allows precise determination of the position and deployment status of the device. On contrast-enhanced images the occlusion status of aneurysms and the positioning of the WEB in relationship to the parent artery can be evaluated. C-arm-CT may serve as a minimal-invasive follow-up imaging modality.

摘要

简介

采用平板探测器血管造影(FD-CT)系统的血管造影 C 臂 CT 成像性能的提高,现在为治疗颅内动脉瘤所用装置的体内可视化提供了一种手段。WEB 栓塞装置是一种由镍钛合金丝编织而成的网状物,其大小接近常规 X 射线透视的可视化极限。我们的假设是,这些植入物的 C 臂 CT 成像将提供有关其定位和部署的有用信息。

方法

在 5 只新西兰白兔中,通过弹性蛋白酶诱导动脉瘤,然后使用 WEB 进行治疗。使用数字减影血管造影(DSA)、X 射线成像和两种不同的血管造影 C 臂 CT 方案进行成像。两位神经放射学家使用评估量表对图像进行评估。

结果

WEB 的网眼在 DSA 或 X 射线透视图像上几乎不可见。使用 C 臂 CT 方案进行的容积再现技术(VRT)重建和多平面重建(MPR)清楚地描绘了装置的形状和结构。对比增强 MPR 和 VRT 重建允许评估动脉瘤内血流的状态。WEB 上的铂金标记物引起的束硬化伪影存在。

结论

WEB 的体内 C 臂 CT 成像可行,并允许精确确定装置的位置和部署状态。在对比增强图像上,可以评估动脉瘤的闭塞状态和 WEB 相对于母动脉的定位。C 臂 CT 可以作为一种微创随访成像方式。

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本文引用的文献

1
WEB device for endovascular treatment of wide-neck bifurcation aneurysms.血管内治疗宽颈分叉动脉瘤的 WEB 装置。
AJNR Am J Neuroradiol. 2013 Jun-Jul;34(6):1209-14. doi: 10.3174/ajnr.A3387. Epub 2013 Jan 4.
2
Intraprocedural angiographic CT as a valuable tool in the course of endovascular treatment of direct sinus cavernous fistulas.术中血管造影CT作为直接海绵窦瘘血管内治疗过程中的一种有价值工具。
Interv Neuroradiol. 2012 Sep;18(3):326-32. doi: 10.1177/159101991201800313. Epub 2012 Sep 10.
3
Measurement of quantifiable parameters by time-density curves in the elastase-induced aneurysm model: first results in the comparison of a flow diverter and a conventional aneurysm stent.
High-Resolution C-Arm CT and Metal Artifact Reduction Software: A Novel Imaging Modality for Analyzing Aneurysms Treated with Stent-Assisted Coil Embolization.
高分辨率C型臂CT与金属伪影减少软件:一种用于分析支架辅助弹簧圈栓塞治疗动脉瘤的新型成像方式。
AJNR Am J Neuroradiol. 2016 Feb;37(2):317-23. doi: 10.3174/ajnr.A4509. Epub 2015 Sep 10.
4
Metal artifact reduction for flat panel detector intravenous CT angiography in patients with intracranial metallic implants after endovascular and surgical treatment.血管内及外科治疗后颅内金属植入物患者平板探测器静脉CT血管造影的金属伪影减少
J Neurointerv Surg. 2016 Aug;8(8):824-9. doi: 10.1136/neurintsurg-2015-011787. Epub 2015 Sep 7.
5
From bench to bedside: utility of the rabbit elastase aneurysm model in preclinical studies of intracranial aneurysm treatment.从实验台到临床:兔弹性蛋白酶诱导动脉瘤模型在颅内动脉瘤治疗临床前研究中的应用
J Neurointerv Surg. 2016 May;8(5):521-5. doi: 10.1136/neurintsurg-2015-011704. Epub 2015 Apr 22.
通过弹性蛋白酶诱导的动脉瘤模型中的时间密度曲线测量可量化参数:血流导向装置与传统动脉瘤支架比较的初步结果。
Eur Radiol. 2013 Feb;23(2):521-7. doi: 10.1007/s00330-012-2611-2. Epub 2012 Aug 16.
4
Coiling after treatment with the woven EndoBridge cerebral aneurysm embolization device. A case report.使用编织型EndoBridge脑动脉瘤栓塞装置治疗后的弹簧圈栓塞。病例报告。
Interv Neuroradiol. 2012 Jun;18(2):208-12. doi: 10.1177/159101991201800214. Epub 2012 Jun 4.
5
Intrasaccular flow-disruption treatment of intracranial aneurysms: preliminary results of a multicenter clinical study.颅内动脉瘤的腔内血流阻断治疗:多中心临床研究的初步结果。
AJNR Am J Neuroradiol. 2012 Aug;33(7):1232-8. doi: 10.3174/ajnr.A3191. Epub 2012 Jun 7.
6
Optimized angiographic computed tomography with intravenous contrast injection: an alternative to conventional angiography in the follow-up of clipped aneurysms?静脉注射对比剂的优化血管造影计算机断层扫描:在夹闭动脉瘤的随访中替代传统血管造影的方法?
J Neurosurg. 2012 Jul;117(1):29-36. doi: 10.3171/2012.3.JNS111895. Epub 2012 Apr 20.
7
Angiographic CT for intraprocedural monitoring of complex neuroendovascular procedures.血管造影 CT 用于复杂神经血管内程序的术中监测。
AJNR Am J Neuroradiol. 2013 Jul;34(7):E77-80. doi: 10.3174/ajnr.A3014. Epub 2012 Apr 5.
8
Angiographic CT with intravenous contrast agent application for monitoring of intracranial flow diverting stents.血管造影 CT 静脉内造影剂应用于颅内血流导向支架监测。
Neuroradiology. 2012 Jul;54(7):727-35. doi: 10.1007/s00234-011-0965-9. Epub 2011 Oct 4.
9
Feasibility of flat panel angiographic CT after intravenous contrast agent application in the postoperative evaluation of patients with clipped aneurysms.静脉应用对比剂后平板血管造影 CT 在夹闭动脉瘤术后评估中的可行性。
AJNR Am J Neuroradiol. 2011 Nov-Dec;32(10):1956-62. doi: 10.3174/ajnr.A2611. Epub 2011 Aug 18.
10
Intravenous flat detector CT angiography for non-invasive visualisation of intracranial flow diverter: technical feasibility.颅内血流导向装置的无创可视化:静脉平板探测器 CT 血管造影的技术可行性。
Eur Radiol. 2011 Aug;21(8):1797-801. doi: 10.1007/s00330-011-2113-7. Epub 2011 Mar 30.