Department of Neuroradiology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany,
Clin Neuroradiol. 2014 Mar;24(1):43-9. doi: 10.1007/s00062-013-0224-z. Epub 2013 May 28.
Improvements in the imaging capabilities of angiographic C-arm computed tomography (CT) using flat detector angiographic (FD-CT) systems now provide a means for the in vivo visualization of devices used for the treatment of intracranial aneurysms. One such device, the WEB embolization device, is made of a braided mesh of nitinol wires, the size of which are near to the limits of visualization using conventional x-ray fluoroscopy. Our hypothesis was that the imaging of these implants C-arm CT would provide useful information regarding their positioning and deployment.
In five New Zealand white rabbits elastase induced aneurysms were created and subsequently treated using a WEB. Imaging was performed using digital subtraction angiography (DSA), X-ray imaging and two different Angiographic C-arm CT protocols. The images were evaluated by two neuroradiologists using an evaluation scale.
The mesh of the WEB was barely visible on the DSA or x-ray fluoroscopy images. Volume rendering technique (VRT) reconstruction and multiplanar reconstruction (MPR) of images done using the C-arm CT protocols clearly delineated the shape and structure of the device. Contrast-enhanced MPR and VRT reconstructions allowed assessment of the status of blood flow in the aneurysms. Beam hardening artifacts caused by platinum markers on the WEB were present.
In vivo C-arm CT imaging of the WEB is feasible and allows precise determination of the position and deployment status of the device. On contrast-enhanced images the occlusion status of aneurysms and the positioning of the WEB in relationship to the parent artery can be evaluated. C-arm-CT may serve as a minimal-invasive follow-up imaging modality.
采用平板探测器血管造影(FD-CT)系统的血管造影 C 臂 CT 成像性能的提高,现在为治疗颅内动脉瘤所用装置的体内可视化提供了一种手段。WEB 栓塞装置是一种由镍钛合金丝编织而成的网状物,其大小接近常规 X 射线透视的可视化极限。我们的假设是,这些植入物的 C 臂 CT 成像将提供有关其定位和部署的有用信息。
在 5 只新西兰白兔中,通过弹性蛋白酶诱导动脉瘤,然后使用 WEB 进行治疗。使用数字减影血管造影(DSA)、X 射线成像和两种不同的血管造影 C 臂 CT 方案进行成像。两位神经放射学家使用评估量表对图像进行评估。
WEB 的网眼在 DSA 或 X 射线透视图像上几乎不可见。使用 C 臂 CT 方案进行的容积再现技术(VRT)重建和多平面重建(MPR)清楚地描绘了装置的形状和结构。对比增强 MPR 和 VRT 重建允许评估动脉瘤内血流的状态。WEB 上的铂金标记物引起的束硬化伪影存在。
WEB 的体内 C 臂 CT 成像可行,并允许精确确定装置的位置和部署状态。在对比增强图像上,可以评估动脉瘤的闭塞状态和 WEB 相对于母动脉的定位。C 臂 CT 可以作为一种微创随访成像方式。