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ZNF668 functions as a tumor suppressor by regulating p53 stability and function in breast cancer.
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BRIT1 regulates p53 stability and functions as a tumor suppressor in breast cancer.
Carcinogenesis. 2013 Oct;34(10):2271-80. doi: 10.1093/carcin/bgt190. Epub 2013 Jun 1.
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UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.
J Pathol. 2015 Mar;235(4):656-67. doi: 10.1002/path.4478. Epub 2015 Jan 7.
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Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase.
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RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage.
Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4579-84. doi: 10.1073/pnas.0912094107. Epub 2010 Feb 19.
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ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.
EMBO J. 2009 Dec 16;28(24):3857-67. doi: 10.1038/emboj.2009.294.
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ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
EMBO J. 2005 Oct 5;24(19):3411-22. doi: 10.1038/sj.emboj.7600812. Epub 2005 Sep 15.

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Nucleolar URB1 ensures 3' ETS rRNA removal to prevent exosome surveillance.
Nature. 2023 Mar;615(7952):526-534. doi: 10.1038/s41586-023-05767-5. Epub 2023 Mar 8.

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Rak functions as a tumor suppressor by regulating PTEN protein stability and function.
Cancer Cell. 2009 Apr 7;15(4):304-14. doi: 10.1016/j.ccr.2009.02.012.
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Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Res. 2009 Jan;37(Database issue):D925-32. doi: 10.1093/nar/gkn730. Epub 2008 Oct 15.
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NUMB controls p53 tumour suppressor activity.
Nature. 2008 Jan 3;451(7174):76-80. doi: 10.1038/nature06412.
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The genomic landscapes of human breast and colorectal cancers.
Science. 2007 Nov 16;318(5853):1108-13. doi: 10.1126/science.1145720. Epub 2007 Oct 11.
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Depletion of the nucleolar protein nucleostemin causes G1 cell cycle arrest via the p53 pathway.
Mol Biol Cell. 2007 Jul;18(7):2630-5. doi: 10.1091/mbc.e07-03-0244. Epub 2007 May 9.
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The consensus coding sequences of human breast and colorectal cancers.
Science. 2006 Oct 13;314(5797):268-74. doi: 10.1126/science.1133427. Epub 2006 Sep 7.
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Balancing Mdm2 - a Daxx-HAUSP matter.
Nat Cell Biol. 2006 Aug;8(8):790-1. doi: 10.1038/ncb0806-790.
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A second p53 binding site in the central domain of Mdm2 is essential for p53 ubiquitination.
Biochemistry. 2006 Aug 1;45(30):9238-45. doi: 10.1021/bi060661u.
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Dual-site regulation of MDM2 E3-ubiquitin ligase activity.
Mol Cell. 2006 Jul 21;23(2):251-63. doi: 10.1016/j.molcel.2006.05.029.
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Regulation of the MDM2-p53 pathway by ribosomal protein L11 involves a post-ubiquitination mechanism.
J Biol Chem. 2006 Aug 25;281(34):24304-13. doi: 10.1074/jbc.M602596200. Epub 2006 Jun 27.

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