Metabolism and Body Composition Laboratory, Department of Kinesiology, University of Georgia, Athens, Georgia 30602-6554, USA.
J Appl Physiol (1985). 2011 Dec;111(6):1584-9. doi: 10.1152/japplphysiol.00416.2011. Epub 2011 Aug 18.
High postprandial blood triglyceride (TG) levels increase cardiovascular disease risk. Exercise interventions may be effective in reducing postprandial blood TG. The purpose of this study was to determine the effects of sprint interval cycling (SIC), with and without replacement of the energy deficit, on postprandial lipemia. In a repeated-measures crossover design, six men and six women participated in three trials, each taking place over 2 days. On the evening of the first day of each trial, the participants either did SIC without replacing the energy deficit (Ex-Def), did SIC and replaced the energy deficit (Ex-Bal), or did not exercise (control). SIC was performed on a cycle ergometer and involved four 30-s all-out sprints with 4-min active recovery. In the morning of day 2, responses to a high-fat meal were measured. Venous blood samples were collected in the fasted state and at 0, 30, 60, 120, and 180 min postprandial. There was a trend toward a reduction with treatment in fasting TG (P = 0.068), but no significant treatment effect for fasting insulin, glucose, nonesterified fatty acids, or betahydroxybutryrate (P > 0.05). The postprandial area under the curve (mmol·l(-1)·3 h(-1)) TG response was significantly lower in Ex-Def (21%, P = 0.006) and Ex-Bal (10%, P = 0.044) than in control, and significantly lower in Ex-Def (12%, P = 0.032) than in Ex-Bal. There was no treatment effect (P > 0.05) observed for area under the curve responses of insulin, glucose, nonesterified fatty acids, or betahydroxybutryrate. SIC reduces postprandial lipemia, but the energy deficit alone does not fully explain the decrease observed.
餐后血液三酰甘油（TG）水平升高会增加心血管疾病风险。运动干预可能有助于降低餐后血液 TG。本研究旨在确定冲刺间歇骑行（SIC），无论是否替代能量亏空，对餐后脂血症的影响。在重复测量交叉设计中，六名男性和六名女性参加了三项试验，每项试验持续两天。在每项试验的第一天晚上，参与者要么进行不替代能量亏空的 SIC（Ex-Def），要么进行 SIC 并替代能量亏空（Ex-Bal），要么不运动（对照）。SIC 在自行车测功仪上进行，包括四个 30 秒的全力冲刺，有 4 分钟的主动恢复期。在第二天早上，测量了高脂肪餐后的反应。空腹和餐后 0、30、60、120 和 180 分钟采集静脉血样。尽管治疗有降低空腹 TG 的趋势（P = 0.068），但空腹胰岛素、葡萄糖、非酯化脂肪酸或β-羟丁酸（P > 0.05）没有显著的治疗效果。与对照相比，Ex-Def（21%，P = 0.006）和 Ex-Bal（10%，P = 0.044）的餐后 TG 曲线下面积（mmol·l(-1)·3 h(-1))反应显著降低，且 Ex-Def（12%，P = 0.032）的降低幅度显著大于 Ex-Bal。胰岛素、葡萄糖、非酯化脂肪酸或β-羟丁酸的曲线下面积反应没有观察到治疗效果（P > 0.05）。SIC 可降低餐后脂血症，但单独的能量亏空并不能完全解释观察到的下降。
