Polo、长城蛋白和蛋白磷酸酶PP2A争夺首要地位。 - Suppr

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超能文献

Polo, greatwall, and protein phosphatase PP2A Jostle for pole position.

作者信息

Boke Elvan, Hagan Iain M

机构信息

CRUK Cell Division Group, Paterson Institute for Cancer Research, Manchester, United Kingdom.

出版信息

PLoS Genet. 2011 Aug;7(8):e1002213. doi: 10.1371/journal.pgen.1002213. Epub 2011 Aug 11.

DOI:10.1371/journal.pgen.1002213

PMID:21852954

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3154949/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9ba/3154949/c7fb9672690b/pgen.1002213.g001.jpg

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本文引用的文献

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Regulation of Greatwall kinase during Xenopus oocyte maturation.沃尔夫冈激酶在爪蟾卵母细胞成熟过程中的调控作用。

Mol Biol Cell. 2011 Jul 1;22(13):2157-64. doi: 10.1091/mbc.E11-01-0008. Epub 2011 May 5.

The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A.长城激酶的底物 Arpp19 通过抑制蛋白磷酸酶 2A 来控制有丝分裂。

Science. 2010 Dec 17;330(6011):1673-7. doi: 10.1126/science.1197048.

Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis.长城激酶磷酸化了一种蛋白磷酸酶 2A 的抑制剂，这种抑制剂对于有丝分裂是必需的。

Science. 2010 Dec 17;330(6011):1670-3. doi: 10.1126/science.1195689.

Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.活细胞成像 RNAi 筛选鉴定出 PP2A-B55alpha 和 importin-beta1 是人细胞有丝分裂退出的关键调节因子。

Nat Cell Biol. 2010 Sep;12(9):886-93. doi: 10.1038/ncb2092. Epub 2010 Aug 15.

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Greatwall maintains mitosis through regulation of PP2A.长城通过调节蛋白磷酸酶2A维持有丝分裂。

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