Division of Pediatric Oncology, Department of Oncology, Johns Hopkins University, Baltimore, Maryland 21287, USA.
Pediatr Blood Cancer. 2012 Jul 15;59(1):179-81. doi: 10.1002/pbc.23321. Epub 2011 Aug 18.
Cardiac metastasis and hypertrophic osteoarthropathy are both quite rare. We describe a patient presenting with hypertrophic osteoarthropathy as the first symptom of recurrent infantile fibrosarcoma (IF). During surgical resection of lung metastasis, the patient suffered sudden cardiac arrest. Autopsy demonstrated a metastatic lesion in the intraventricular septum of the heart, which is previously undescribed in the literature. This case demonstrates that IF can be aggressive despite its more typical benign course.
心脏转移和肥大性骨关节病均较为罕见。我们描述了一例以肥大性骨关节病为首发症状的复发性婴儿纤维肉瘤(IF)患者。在肺转移灶切除手术中,患者突发心脏骤停。尸检显示心脏室间隔有转移病灶,这在文献中尚无报道。该病例表明,尽管 IF 通常表现为良性,但也可能具有侵袭性。