Linz Institute for Organic Solar Cells (LIOS), Johannes Kepler University Linz, Alltenberger Strasse 69, A-4040 Linz, Austria.
J Phys Chem B. 2011 Sep 29;115(38):11199-207. doi: 10.1021/jp2033577. Epub 2011 Sep 2.
The capability to monitor finely the physical properties of eumelanin, an important class of biopolymers, involved in melanoma cancer pathologies, whose function and intrinsic disorder still collects the interest of many investigators, was achieved by means of electrospray deposition (ESD). By alleviating the problem of the solubility of melanin through the realization of high-quality films it was possible to spread light on the unknown biopolymer supramolecular organization. In fact, on the basis of scanning probe microscopies, electron spectroscopies, and transport properties, it was possible to delineate peculiar features of the melanin organization varying from heteropolymeric to oligomeric in character and eventually turning in a cross-linked secondary molecular structure.
通过电喷雾沉积（ESD）实现了对生物聚合物黑色素的物理性质进行精细监测的能力，黑色素是参与黑色素瘤癌症病理的重要生物聚合物类别，其功能和固有无序性仍然引起许多研究人员的兴趣。通过实现高质量的薄膜缓解了黑色素的溶解度问题，从而能够揭示未知生物聚合物超分子组织的情况。事实上，基于扫描探针显微镜、电子能谱和输运性质，有可能描绘出黑色素组织的独特特征，这些特征从杂聚物到低聚物性质不等，最终形成交联的二级分子结构。
