Sun Jie, Ding Zhengnian, Qian Yanning
Department of Anesthesiology, First Affiliated Hospital with Nanjing Medical University/Jiangsu province hospital, Nanjing, P.R.,China.
J Cardiothorac Surg. 2011 Aug 19;6:99. doi: 10.1186/1749-8090-6-99.
The objective of this study was to investigate the effect of beta blocker on cardiac recovery and rhythm during cardiac surgeries. Sixty surgical rheumatic heart disease patients were received esmolol 1 mg/kg or the same volume of saline prior to removal of the aortic clamp. The incidence of cardiac automatic re-beat, ventricular fibrillation after reperfusion, the heart rate after steady re-beat, vasoactive drug use during weaning from bypass, the posterior parallel time and total bypass time were decreased by esmolol treatment.
Esmolol has a positive effect on the cardiac recovery in cardiopulmonary bypass surgeries.
本研究的目的是调查β受体阻滞剂对心脏手术期间心脏恢复和节律的影响。60例风湿性心脏病手术患者在松开主动脉夹之前接受了艾司洛尔1mg/kg或相同体积的生理盐水。艾司洛尔治疗降低了心脏自动复跳、再灌注后室颤的发生率、稳定复跳后的心率、脱离体外循环期间血管活性药物的使用、后并行时间和总体外循环时间。
艾司洛尔在体外循环手术中对心脏恢复有积极作用。