Navaravong Leenhapong, Ali Ronan G, Giugliano Gregory R
Cardiovascular Division, Baystate Medical Center, Springfield, MA 01199, USA.
Cardiovasc Revasc Med. 2011 Nov-Dec;12(6):399-402. doi: 10.1016/j.carrev.2011.05.002. Epub 2011 Aug 19.
Atherosclerotic renal artery disease is a common disease entity that may be identified in patients with difficult-to-control hypertension and/or chronic kidney disease but is probably underdiagnosed. Current evidence from both observational and randomized studies offers mixed results regarding the support for renal artery revascularization. There is lack of equipoise with regard to the efficacy of renal artery revascularization among the interventional and renal communities, as well as disagreements on the appropriate endpoints to measure in clinical trials, which have led to selection bias confounding the scant available data. We report a patient who does not fit any clinical trial inclusion criteria with acute on chronic kidney injury and new-onset heart failure whose symptoms and renal function improved significantly after renal artery intervention.
动脉粥样硬化性肾动脉疾病是一种常见的疾病实体，可能在难以控制的高血压和/或慢性肾脏病患者中被发现，但可能诊断不足。观察性研究和随机研究的现有证据对于肾动脉血运重建的支持结果不一。在介入治疗界和肾脏学界之间，对于肾动脉血运重建的疗效缺乏平衡，在临床试验中应测量的适当终点方面也存在分歧，这导致选择偏倚混淆了现有的少量数据。我们报告了一名不符合任何临床试验纳入标准的患者，该患者患有急性慢性肾损伤和新发心力衰竭，在肾动脉介入治疗后症状和肾功能显著改善。
