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加拿大儿童癫痫患病率。

Prevalence of childhood epilepsy in Canada.

机构信息

Department of Pediatrics, University of Western Ontario, London, Ontario, Canada.

出版信息

Can J Neurol Sci. 2011 Sep;38(5):719-22. doi: 10.1017/s0317167100054081.

DOI:10.1017/s0317167100054081
PMID:21856574
Abstract

RATIONALE

Few data exist on the frequency and burden of childhood epilepsy in Canada and on the impact in the general population. We have assessed the point prevalence of childhood epilepsy in Canada.

METHODS

We analyzed data from the National Longitudinal Survey of Children and Youth (N=20 025 for Cycle 2, and N= 31 960 for cycle 3). Each cycle was collected over a two year period (2: 1996-1997, 3: 1998-1999). In the survey the following specific question was asked to the person most knowledgeable in the household: "Does the child have any of the following long-term conditions that have been diagnosed by a health professional?" The list of responses included Epilepsy and certain co-morbid conditions. In addition, a subsequent question identified whether the condition was treated by means of a specific anticonvulsant medication. (anticonvulsants or anti-epileptic pills?). Prevalence was based on the national standard population at the time of each survey.

RESULTS

In Cycle 2, 80 of 20 025 subjects from 0 to 13 years old were described to have the diagnosis of epilepsy, yielding a weighted point prevalence of 4.03 per 1 000. In Cycle 3 161 of 31 960 children from 0 to 15 were described as having epilepsy, yielding a weighted point prevalence of 5.26 per 1 000. The rate of epilepsy was higher for males and increases with age.

CONCLUSION

The overall rates for this age cohort are consistent with those obtained in other developed countries and seem to coincide with rates for youth and adults in Canada.

摘要

背景

加拿大有关儿童癫痫的发病率和负担以及对普通人群影响的数据有限。我们评估了加拿大儿童癫痫的时点患病率。

方法

我们分析了全国儿童纵向研究(N=20025 人,第 2 周期;N=31960 人,第 3 周期)的数据。每个周期的采集时间跨度为两年(2:1996-1997;3:1998-1999)。在调查中,向家庭中最了解情况的人询问了以下具体问题:“孩子是否患有以下任何一种由医疗保健专业人员诊断的长期疾病?”答复清单包括癫痫和某些合并症。此外,下一个问题确定了该病症是否通过特定的抗癫痫药物(抗癫痫药或抗癫痫药?)进行治疗。患病率基于每个调查时的全国标准人口。

结果

第 2 周期中,20025 名 0 至 13 岁的研究对象中有 80 人被描述为患有癫痫,加权时点患病率为每 1000 人 4.03。第 3 周期中,31960 名 0 至 15 岁的儿童中有 161 人被描述为患有癫痫,加权时点患病率为每 1000 人 5.26。癫痫的发病率男性较高,并随年龄增长而增加。

结论

该年龄段的总体发病率与其他发达国家的结果一致,似乎与加拿大青年和成年人的发病率一致。

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