Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4399, USA.
Br J Anaesth. 2011 Nov;107(5):790-5. doi: 10.1093/bja/aer263. Epub 2011 Aug 19.
Umbilical hernia repair, a common day-surgery procedure in children, is associated with considerable postoperative discomfort. Possible modes of postoperative analgesia for umbilical hernia repair are rectus sheath block (RSB) and local anaesthetic infiltration of the surgical site (LAI).
We undertook an observer-blinded, randomized, prospective, observational study to compare the efficacy of ultrasound-guided RSB and LAI in providing postoperative analgesia for umbilical hernia repair. Our primary objective was to compare the use of opioid medication between patients who receive RSB and those who receive LAI. Our secondary objectives were to compare the duration of analgesia based on time to first rescue analgesic, to compare the quality of analgesia based on revised FACES scale, and to determine the incidence of side-effects.
Fifty-two patients (26 in each group) completed the study. There was a statistically significant difference in the perioperative opioid medication consumption between the LAI group [mean: 0.13 mg kg(-1), confidence interval (0.09-0.17 mg kg⁻¹)] and the RSB group [mean: 0.07 mg kg⁻¹, confidence interval (0.05-0.09 mg kg⁻¹)] (P=0.008). When we compared the postoperative opioid consumption between the LAI group [mean: 0.1 mg kg⁻¹, 95% confidence interval (0.07-0.13 mg kg⁻¹)] and the RSB group [mean: 0.07 mg kg(-1), 95% confidence interval (0.05-0.09 mg kg⁻¹)] (P=0.09), there was a trend towards statistical significance between the two groups. The difference in time to rescue analgesic administration between the RSB group [49.7 (36.9) min] and the LAI group [32.4 (29.4) min] was not statistically significant (P=0.11).
This study demonstrates that ultrasound-guided RSB provides superior analgesia in the perioperative period compared with infiltration of the surgical site after umbilical hernia repair. In comparing only the postoperative period, analgesia provided by an ultrasound-guided RSB showed a trend towards statistically significant improvement compared with infiltration of the surgical site.
脐疝修补术是儿童常见的日间手术,术后会出现明显的不适。脐疝修补术后可能的镇痛方式包括腹直肌鞘阻滞(RSB)和手术部位局部麻醉浸润(LAI)。
我们进行了一项观察者盲法、随机、前瞻性、观察性研究,比较超声引导下 RSB 和 LAI 在脐疝修补术后提供镇痛的效果。我们的主要目标是比较接受 RSB 和 LAI 的患者之间使用阿片类药物的情况。我们的次要目标是比较基于首次解救镇痛时间的镇痛持续时间,比较基于修订后的 FACES 量表的镇痛质量,并确定不良反应的发生率。
52 名患者(每组 26 名)完成了研究。LAI 组[平均:0.13 mg/kg,置信区间(0.09-0.17 mg/kg)]和 RSB 组[平均:0.07 mg/kg,置信区间(0.05-0.09 mg/kg)]在围手术期阿片类药物的使用方面有统计学显著差异(P=0.008)。当我们比较 LAI 组[平均:0.10 mg/kg,95%置信区间(0.07-0.13 mg/kg)]和 RSB 组[平均:0.07 mg/kg,95%置信区间(0.05-0.09 mg/kg)]的术后阿片类药物消耗时,两组之间有统计学意义的趋势(P=0.09)。RSB 组[49.7(36.9)分钟]和 LAI 组[32.4(29.4)分钟]之间解救镇痛给药时间的差异无统计学意义(P=0.11)。
本研究表明,与脐疝修补术后手术部位浸润相比,超声引导下 RSB 可提供更好的围手术期镇痛。仅比较术后期间,超声引导下 RSB 提供的镇痛与手术部位浸润相比,有统计学意义的改善趋势。