托尔克（TolC）影响霍乱弧菌的毒力基因表达。
TolC affects virulence gene expression in Vibrio cholerae.
机构信息
Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon 97331-4801, USA.
出版信息
J Bacteriol. 2011 Oct;193(20):5850-2. doi: 10.1128/JB.05222-11. Epub 2011 Aug 19.
Abstract
A Vibrio cholerae tolC mutant showed increased toxT expression in M9 medium, but not in the presence of four amino acids that induce cholera toxin production, and in LB with high osmolarity but not high pH or temperature. TolC did not affect expression of other regulatory genes in the ToxR regulon.
摘要
一株霍乱弧菌 tolC 突变株在 M9 培养基中表现出 toxT 表达增加，但在诱导霍乱毒素产生的四种氨基酸存在下、在 LB 高渗透压但不在高 pH 值或高温下则没有增加。TolC 不影响 ToxR 调控子中其他调节基因的表达。
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