Waters Hugh R, Korn Roy, Colantuoni Elizabeth, Berenholtz Sean M, Goeschel Christine A, Needham Dale M, Pham Julius C, Lipitz-Snyderman Allison, Watson Sam R, Posa Patricia, Pronovost Peter J
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Am J Med Qual. 2011 Sep-Oct;26(5):333-9. doi: 10.1177/1062860611410685.
Health care-associated infections affect an estimated 5% of hospitalized patients and represent one of the leading causes of illness and death in the United States. This study calculates the costs and benefits of a patient safety program in intensive care units in 6 hospitals that were part of the Michigan Keystone ICU Patient Safety Program. On average, 29.9 catheter-related bloodstream infections and 18.0 cases of ventilator-associated pneumonia were averted per hospital on an annual basis. The average cost of the intervention is $3375 per infection averted, measured in 2007 dollars. The cost of the intervention is substantially less than estimates of the additional health care costs associated with these infections, which range from $12 208 to $56 167 per infection episode. These results do not take into account the additional effect of the Michigan Keystone program in terms of reducing cases of sepsis or its effects in terms of preventing mortality, improving teamwork, and reducing nurse turnover.
医疗保健相关感染估计影响5%的住院患者，是美国疾病和死亡的主要原因之一。本研究计算了密歇根州重点重症监护病房患者安全项目中6家医院重症监护病房患者安全项目的成本和效益。每家医院每年平均避免29.9例导管相关血流感染和18.0例呼吸机相关性肺炎。以2007年美元计算，避免每例感染的干预平均成本为3375美元。干预成本远低于与这些感染相关的额外医疗保健成本估计，每例感染事件的额外医疗保健成本估计在12208美元至56167美元之间。这些结果没有考虑密歇根州重点项目在减少脓毒症病例方面的额外效果，或其在预防死亡、改善团队合作和减少护士流失方面的效果。
