EaStCHEM School of Chemistry, University of St Andrews, St Andrews, KY16 9ST, UK.
Org Biomol Chem. 2011 Oct 21;9(20):7038-41. doi: 10.1039/c1ob06112g. Epub 2011 Aug 22.
The synthesis and catalytic activity of three well-defined monomeric rhodium(I) hydroxide complexes bearing N-heterocyclic carbene (NHC) ligands are reported. [Rh(cod)(ICy)(OH)] promoted the 1,4-addition of arylboronic acids to cyclic enones, with TONs and TOFs of 100,000 and 6,600 h(-1), respectively, at 0.001 mol% catalyst loadings. Mechanistic studies permitted the isolation of a phenylrhodium intermediate.
报告了三种结构明确的单核铑（I）氢氧化物配合物的合成及其作为 N-杂环卡宾（NHC）配体的催化活性。[Rh(cod)(ICy)(OH)]促进了芳基硼酸对环状烯酮的 1,4-加成反应，在 0.001 mol%催化剂负载量下，TON 和 TOF 分别达到 100,000 和 6,600 h(-1)。机理研究允许分离出一个苯基铑中间体。
