Department of Entomology, China Agricultural University, Beijing 100193, China.
Pest Manag Sci. 2012 Feb;68(2):285-9. doi: 10.1002/ps.2258. Epub 2011 Aug 19.
Fufenozide is a novel non-steroidal ecdysone agonist with good efficacy against diamondback moth (DBM), Plutella xylostella (Lepidoptera: Plutellidae). At present, it is widely applied for the control of a range of lepidopterous pests in China. This study compared the activities of fufenozide and 12 other insecticides against unselected and fufenozide-selected strains of DBM to examine potential patterns of cross-resistance. The relative fitness of the fufenozide-selected strain was assessed to provide information pertinent to insecticide resistance management.
Compared with the susceptible strain (JSS), the fufenozide-resistant strain (JSR) showed high cross-resistance to dibenzoylhydrazines and benzoylphenylureas, low cross-resistance to abamectin and no cross-resistance to organophosphates, carbamates and pyrethroids. JSR had a lower reproductive ability and a relative fitness of 0.5 compared with JSS.
P. xylostella has the potential to develop resistance to fufenozide, albeit at the expense of fitness. Cross-resistance between the same and other classes of insecticides is of concern, and should be a key consideration when implementing fufenozide-based control strategies for this species.
抑食肼是一种新型的非甾体蜕皮激素激动剂，对小菜蛾（鳞翅目：菜蛾科）具有良好的防治效果。目前，它在中国被广泛应用于防治多种鳞翅目害虫。本研究比较了抑食肼和其他 12 种杀虫剂对未经选择和抑食肼选择的小菜蛾种群的活性，以检验潜在的交互抗性模式。评估了抑食肼选择株的相对适合度，为杀虫剂抗性管理提供相关信息。
与敏感株（JSS）相比，抑食肼抗性株（JSR）对二苯甲酰肼和苯甲酰基苯基脲表现出高交互抗性，对阿维菌素表现出低交互抗性，对有机磷、氨基甲酸酯和拟除虫菊酯没有交互抗性。与 JSS 相比，JSR 的繁殖能力较低，相对适合度为 0.5。
小菜蛾有可能对抑食肼产生抗性，尽管这是以牺牲适合度为代价的。同一类和其他类杀虫剂之间的交互抗性令人担忧，在实施基于抑食肼的防治策略时应重点考虑。
