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首次精神科住院后的死亡率变化:一项为期20年的前瞻性纵向临床研究。

Changes in mortality after first psychiatric admission: a 20-year prospective longitudinal clinical study.

作者信息

Nome Siri, Holsten Fred

机构信息

Centre for Research and Education in Forensic Psychiatry, Haukeland University Hospital, Sandviken, Bergen, Norway.

出版信息

Nord J Psychiatry. 2012 Apr;66(2):97-106. doi: 10.3109/08039488.2011.605170. Epub 2011 Aug 23.

Abstract

OBJECTIVE

To examine changes in the mortality of patients admitted to a Norwegian psychiatric hospital from 1985 to 2003: this period saw profound changes in structure and organization of the mental healthcare system.

METHOD

A 20-year prospective longitudinal, record linkage study of all patients admitted to a psychiatric hospital with sector responsibility from 1985 to 2003.

RESULTS

Excess mortality was found for the patient group. Overall standardized mortality ratio (SMR) (95% confidence interval, CI) was 2.85 (2.53-3.07)/2.15 (1.94-2.41) for male/female patients. One third of the patients who died in the study period died within 2 years after first admission, and 45% of the deaths happened within 2 years after last discharge. The median age at death decreased in the study period for patients who were younger than 65 years at their first admission. The median difference of lost years of life for the patients younger than 65 years at first admittance was 26.95/23.96 years for male/female patients. SMR increased for the youngest cohorts during the study period over time. From 1985 to 2003, SMR increased dramatically for both genders.

CONCLUSION

Patients admitted to a Norwegian psychiatric hospital for their first stay during 1985-2003 suffered increased excess mortality, whereas mortality in the general population decreased. The mortality was highest in the first 2 years after admission. Despite profound changes in the mental healthcare system, the mortality gap increased in the study period and was highest in the youngest birth cohorts.

摘要

目的

研究1985年至2003年期间入住挪威一家精神病医院患者的死亡率变化情况,在此期间精神卫生保健系统的结构和组织发生了深刻变革。

方法

对1985年至2003年期间入住一家承担部门责任的精神病医院的所有患者进行了一项为期20年的前瞻性纵向记录链接研究。

结果

发现患者组存在超额死亡率。男性/女性患者的总体标准化死亡率(SMR)(95%置信区间,CI)为2.85(2.53 - 3.07)/2.15(1.94 - 2.41)。在研究期间死亡的患者中有三分之一在首次入院后2年内死亡,45%的死亡发生在最后一次出院后2年内。首次入院时年龄小于65岁的患者在研究期间死亡年龄中位数有所下降。首次入院时年龄小于65岁的患者预期寿命损失年数的中位数,男性/女性患者分别为26.95/23.96年。在研究期间,最年轻队列的SMR随时间增加。从1985年到2003年,男女两性的SMR均大幅上升。

结论

1985 - 2003年期间首次入住挪威精神病医院的患者超额死亡率增加,而普通人群的死亡率下降。入院后的头两年死亡率最高。尽管精神卫生保健系统发生了深刻变革,但在研究期间死亡率差距仍在扩大,且在最年轻的出生队列中最高。

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