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比较局限性和节段性喉内收肌痉挛患者的临床特征。

Comparison of clinical characteristics of patients with adductor laryngeal dystonia in the focal and segmental types.

机构信息

Medical doctor, doctoral degree in sciences, Otorhinolaryngology and Head & Neck Surgery Department, São Paulo Federal University, UNIFESP.

Speech therapist, master's degree, specialist in human communications disorders, São Paulo Federal University, UNIFESP. Expert on voice, CEV.

出版信息

Braz J Otorhinolaryngol. 2011 Jul-Aug;77(4):413-417. doi: 10.1590/S1808-86942011000400002.

Abstract

UNLABELLED

Dystonia is a central motor processing neurological disorder characterized by abnormal, often action-induced, involuntary movements or uncontrolled spasms.

AIM

To compare patients with the diagnoses of focal and segmental adductor laryngeal dystonia at the Neurolarynx Outpatient Clinic of the Federal University of São Paulo.

MATERIALS AND METHODS

A clinical retrospective study of data collected from patient registries from 2003 to 2009.

RESULTS

Of 34 patients, 25 presented focal dystonia and 9 presented segmental dystonia. There were 30 females (88. 2%) and 4 males (11. 8%). A relation with a traumatic event was reported in 11 cases (32. 4%). Vocal tremor was observed in 21 patients (61. 8%). The mean age at onset, the age at diagnosis, and time between the onset and the diagnosis were respectively 55, 61. 3 and 6. 3 years. There was no statistical difference between patients with focal laryngeal adductor dystonia and segmental dystonia in the study data.

CONCLUSIONS

There were no statistical differences among patients with focal adductor laryngeal dystonia and segmental dystonia relating to age of onset, age of diagnosis, gender, time between onset and diagnosis, presence of associated tremor, and relation to trauma.

摘要

未加标签

肌张力障碍是一种中枢运动处理神经系统障碍,其特征是异常的、通常是由动作引起的、不自主的运动或不受控制的痉挛。

目的

比较在圣保罗联邦大学神经喉门诊就诊的局灶性和节段性内收性喉肌张力障碍患者。

材料和方法

对 2003 年至 2009 年患者登记册中收集的数据进行临床回顾性研究。

结果

34 名患者中,25 名表现为局灶性肌张力障碍,9 名表现为节段性肌张力障碍。30 名女性(88.2%)和 4 名男性(11.8%)。11 例(32.4%)报告有创伤事件。21 例(61.8%)患者观察到声带震颤。发病年龄、诊断年龄和发病至诊断时间的平均值分别为 55、61.3 和 6.3 岁。局灶性内收性喉肌张力障碍患者和节段性肌张力障碍患者在研究数据中无统计学差异。

结论

局灶性内收性喉肌张力障碍患者和节段性肌张力障碍患者在发病年龄、诊断年龄、性别、发病至诊断时间、伴发震颤和与创伤的关系方面无统计学差异。

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本文引用的文献

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Female predominance in spasmodic dysphonia.痉挛性发声障碍中女性占主导。
J Neurol Neurosurg Psychiatry. 1997 Nov;63(5):688. doi: 10.1136/jnnp.63.5.688.
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Sex prevalence of focal dystonias.局灶性肌张力障碍的性别患病率。
J Neurol Neurosurg Psychiatry. 1996 Feb;60(2):204-5. doi: 10.1136/jnnp.60.2.204.

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