Department of Vascular and Thoracic Surgery, Arnaud de Villeneuve Hospital, Montpellier, France.
J Endovasc Ther. 2011 Aug;18(4):485-90. doi: 10.1583/11-3502.1.
To analyze the impact of stent-graft design on the outcome of endovascular repair of acute traumatic thoracic aortic transection.
Forty-eight patients (38 men; mean age 37 ± 11 years) underwent endovascular repair for an acute traumatic aortic rupture between April 2001 and March 2011. Up to October 2007, 32 patients (mean age 41 ± 16 years; group 1) were treated with the first generation of commercially available thoracic stent-grafts (10 Talent, 20 Excluder/TAG, 2 Zenith). From November 2007, 16 patients (mean age 42 ± 19 years; group 2) were treated with second-generation thoracic stent-grafts (13 Valiant and 3 C-TAG). The 2 groups were statistically comparable. Follow-up computed tomography was performed at 1 week; at 3 and 6 months; and annually thereafter.
In the 2 groups, the mortality rate related to aortic repair was nil. All the patients have completed each of their scheduled follow-up evaluations and CT scans. The morbidity rate was significantly reduced (p = 0.0003) from 18.7% (first generation) to 6.2% (second generation). Type I endoleak (n = 1), inadvertent coverage of the supra-aortic trunks (n = 3), and stent-graft collapse (n = 2) occurred only with the first-generation stent-grafts. One iliac artery rupture occurred with a second-generation stent-graft.
Enhanced stent-graft conformability and more accurate delivery systems have significantly decreased the morbidity of endovascular repair of acute traumatic transection of the thoracic aorta. The increasing clinical experience may also have contributed to improved results.
分析支架移植物设计对急性创伤性胸主动脉夹层血管内修复结果的影响。
2001 年 4 月至 2011 年 3 月期间,48 例(38 例男性;平均年龄 37±11 岁)患者因急性创伤性主动脉破裂接受血管内修复。截至 2007 年 10 月,32 例患者(平均年龄 41±16 岁;第 1 组)接受第一代市售胸主动脉支架移植物(10 个 Talent,20 个 Excluder/TAG,2 个 Zenith)治疗。自 2007 年 11 月起,16 例患者(平均年龄 42±19 岁;第 2 组)接受第二代胸主动脉支架移植物(13 个 Valiant 和 3 个 C-TAG)治疗。两组在统计学上具有可比性。术后第 1 周、第 3 个月、第 6 个月及此后每年进行计算机断层扫描(CT)随访。
两组患者主动脉修复相关死亡率均为零。所有患者均完成了计划的随访评估和 CT 扫描。发病率显著降低(p=0.0003),从第一代的 18.7%降至第二代的 6.2%。仅第一代支架移植物发生 1 例Ⅰ型内漏(n=1)、3 例无意中覆盖主动脉弓分支和 2 例支架移植物塌陷。第二代支架移植物发生 1 例髂动脉破裂。
增强的支架移植物顺应性和更精确的输送系统显著降低了急性创伤性胸主动脉夹层血管内修复的发病率。不断增加的临床经验也可能有助于改善结果。