Department of Surgery, Vascular and Endovascular Surgery Unit, University of Siena, Siena, Italy.
J Endovasc Ther. 2011 Aug;18(4):540-4. doi: 10.1583/11-3476.1.
To document a heretofore unreported complication of the contrast agent iodixanol during an endovascular procedure.
A 76-year-old woman with a history of coronary artery disease was admitted to the emergency department for recurrent transient ischemic attacks. Before combined percutaneous transluminal coronary angioplasty and carotid artery stenting (CAS) using iodixanol, the patient suffered from concomitant unstable angina and recurrent transient ischemic attacks. The total amount of iodixanol used during the CAS procedure was 300 mL. Contrast-induced encephalopathy, which manifested as aphasia, stupor, and full hemiparesis immediately after the combined procedure, was diagnosed by urgent computed tomography. Treatment was based on anti-edema drugs, and the patient made a complete recovery within 48 hours, without any neurological sequelae.
Although previously reported in relation to other types of contrast media, contrast-induced encephalopathy has never been described as a complication of an endovascular procedure using iodixanol.
记录在血管内手术期间碘克沙醇造影剂出现的一种此前未曾报道过的并发症。
一名 76 岁女性,有冠心病病史,因反复发作短暂性脑缺血发作而被收入急诊病房。在使用碘克沙醇进行联合经皮腔内冠状动脉血管成形术和颈动脉支架置入术(CAS)前,该患者同时患有不稳定型心绞痛和反复发作短暂性脑缺血发作。在 CAS 手术过程中使用的碘克沙醇总量为 300 毫升。在联合手术后立即出现的造影剂诱导性脑病,表现为言语不清、昏迷和完全偏瘫,通过紧急计算机断层扫描进行诊断。治疗基于抗水肿药物,患者在 48 小时内完全恢复,没有任何神经后遗症。
尽管先前有报道与其他类型的造影剂有关,但造影剂诱导性脑病从未被描述为使用碘克沙醇进行血管内手术的并发症。