Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, No.58 Zhongshan Road 2, Guangzhou, 510080, China.
Department of Neurology, The Seventh Affiliated Hospital, Sun Yat-sen University, No. 628, Xinhun Road, Shenzhen, P. R. China.
BMC Neurol. 2020 Nov 12;20(1):413. doi: 10.1186/s12883-020-01992-x.
Contrast encephalopathy is a rare complication of carotid artery stenting (CAS). Contrast encephalopathy is a diagnosis of exclusion that often needs to be distinguished from high perfusion syndrome, cerebral haemorrhage, subarachnoid haemorrhage (SAH), cerebral infarction and so on.
In this study, we report on a 70-year-old man who was admitted to the hospital with transient ischaemic attacks presenting paroxysmal weakness of limbs in the previous 2 years. He had severe stenosis of the left internal carotid artery diagnosed by digital subtraction angiography (DSA) and underwent CAS. Two hours after the operation, the patient developed paralysis of the right upper limb, unclear speech, fever and restlessness. Emergency skull computed tomography (CT) showed swelling and a linear high-density area in the left cerebral hemisphere. To clarify the components of this high-density area in the traditional CT, the patient had spectral CT, which made the diagnosis of the leakage of contrast clear. After 1 week of supportive treatment, the patient improved.
Spectral CT can easily distinguish the components of high-density areas on traditional CT, which is haemorrhage, calcification or iodine contrast leakage. Therefore, spectral CT is worth consideration for the differential diagnosis of complications of vascular intervention.
对比剂脑病是颈动脉支架置入术(CAS)的罕见并发症。对比剂脑病是一种排除性诊断,常需与高灌注综合征、脑出血、蛛网膜下腔出血(SAH)、脑梗死等相鉴别。
本研究报告了 1 例 70 岁男性患者,因 2 年前出现短暂性脑缺血发作,表现为阵发性四肢无力而入院。数字减影血管造影(DSA)诊断为左侧颈内动脉重度狭窄,行 CAS。术后 2 小时,患者出现右上肢瘫痪、言语不清、发热和烦躁。急诊头颅 CT(CT)显示左大脑半球肿胀伴线性高密度影。为明确传统 CT 高密度影的成分,患者行能谱 CT,明确为对比剂渗漏。经 1 周支持治疗后,患者好转。
能谱 CT 可轻易区分传统 CT 高密度影的成分,即出血、钙化或碘对比剂渗漏。因此,能谱 CT 对血管介入并发症的鉴别诊断具有一定价值。