Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-gu, Seoul 135-710, Republic of Korea.
AJR Am J Roentgenol. 2011 Sep;197(3):W489-94. doi: 10.2214/AJR.10.6319.
The purpose of this article is to prospectively determine the feasibility of using blood oxygenation level-dependent (BOLD) MRI at 3 T in differentiating various renal lesions.
Seventy-one patients (mean age, 53.8 years; range, 22-80 years) underwent kidney MRI, including BOLD MRI at 3 T. BOLD MRI was performed using a multiple fast-field echo (FFE) sequence to acquire 20 T2()-weighted images within a single breath-hold. The rate of spin dephasing (R2()) values of solid and benign cystic renal lesions were compared, and the results of four subgroups--simple cysts, renal cell carcinomas (RCCs), hemorrhagic cysts, and angiomyolipomas (AMLs)--were analyzed. The degree of overall imaging quality in BOLD MRI was also assessed.
One hundred three renal lesions were detected in the 71 patients. The mean (± SD) R2() values of 45 solid lesions (30.6 ± 19.4 1/s) were significantly higher than those of 58 benign cystic lesions (4.5 ± 4.8 1/s; p < 0.001). The mean R2() values of simple cysts, RCCs, hemorrhagic cysts, and AMLs were 1.7 ± 1.7, 22.6 ± 12.6, 10.7 ± 3.7, and 48.0 ± 25.5 1/s, respectively (p < 0.001). The degree of overall imaging quality in all patients was satisfactory or better.
Renal BOLD MRI at 3 T is a feasible technique and may be useful for differentiating various renal lesions.
本文旨在前瞻性地确定使用 3T 血氧水平依赖（BOLD）MRI 区分各种肾脏病变的可行性。
71 例患者（平均年龄 53.8 岁；范围 22-80 岁）接受了肾脏 MRI 检查，包括 3T 的 BOLD MRI。BOLD MRI 使用多次快速场回波（FFE）序列在单次屏气期间采集 20 个 T2()-加权图像。比较实性和良性囊性肾脏病变的自旋去相位率（R2())值，并分析四个亚组（单纯性囊肿、肾细胞癌（RCC）、出血性囊肿和血管平滑肌脂肪瘤（AML））的结果。还评估了 BOLD MRI 的整体成像质量程度。
在 71 例患者中检测到 103 个肾脏病变。45 个实性病变（30.6 ± 19.4 1/s）的平均（±SD）R2()值明显高于 58 个良性囊性病变（4.5 ± 4.8 1/s；p <0.001）。单纯性囊肿、RCC、出血性囊肿和 AML 的平均 R2()值分别为 1.7 ± 1.7、22.6 ± 12.6、10.7 ± 3.7 和 48.0 ± 25.5 1/s（p <0.001）。所有患者的整体成像质量程度均满意或更好。
3T 的肾脏 BOLD MRI 是一种可行的技术，可能有助于区分各种肾脏病变。
