Rehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892-1604, USA.
Am J Phys Med Rehabil. 2011 Oct;90(10):844-50. doi: 10.1097/PHM.0b013e3182240c2c.
The objective of this pilot study was to determine the usability of stereophotogrammetry (SP) as a noninvasive technique for obtaining linear measures and anatomical data of the torso in people with osteogenesis imperfecta in comparison with clinical observations. Ten participants were recruited from subjects enrolled in ongoing institutional review board-approved osteogenesis imperfecta protocols at the National Institute of Child Health and Human Development. Using a Gulick tape measure, anthropometer, and the SP system proprietary software, linear measurements of the torso were taken. In addition, the presence or absence of specific torso deformities was documented from both clinical observation and evaluation of SP images. Measurements of torso diameter and circumference by SP demonstrated strong agreement with the manual measurements (intraclass correlation coefficient = 0.995 and 0.964, respectively). Substantial and statistically significant agreement was present between SP image evaluation and clinical observation for pectus carinatum (κ = 0.52 ± 0.23) and thoracic scoliosis (κ = 0.72 ± 0.12). The kappa values between clinical observation and SP evaluations of other torso deformities were not significant. The strong correlations and P values determined by this study demonstrate the potential value of SP in studying persons with truncal deformities. However, the weak agreement between SP and some clinical observations suggests that further development of SP image analysis tools is required before SP can be used as a standard method of diagnosis or assessment of treatment success.
本初步研究旨在确定体视摄影术（SP）作为一种非侵入性技术，用于获取成骨不全症患者躯干的线性测量值和解剖学数据，与临床观察相比，其可用性如何。从国立儿童健康与人类发展研究所正在进行的机构审查委员会批准的成骨不全症协议中招募了 10 名参与者。使用 Gulick 卷尺、人体测量仪和 SP 系统专用软件，对躯干进行线性测量。此外，从临床观察和 SP 图像评估中记录了特定的躯干畸形的存在或不存在。SP 测量的躯干直径和周长与手动测量值具有很强的一致性（内类相关系数分别为 0.995 和 0.964）。SP 图像评估与临床观察之间在鸡胸（κ=0.52±0.23）和胸脊柱侧凸（κ=0.72±0.12）方面存在显著的一致性。临床观察和 SP 对其他躯干畸形评估之间的κ值不显著。本研究确定的强相关性和 P 值表明 SP 在研究躯干畸形患者方面具有潜在价值。然而，SP 与某些临床观察之间的弱一致性表明，在 SP 可以作为诊断或评估治疗成功的标准方法之前，需要进一步开发 SP 图像分析工具。
