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绝经后出血患者中子宫内膜/子宫体容积比(EV/UCV)预测恶变的价值。

Endometrial/uterine corporeal volume ratio (EV/UCV) as predictor of malignancy in women with postmenopausal bleeding.

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

出版信息

Arch Gynecol Obstet. 2012 Mar;285(3):831-8. doi: 10.1007/s00404-011-2035-2. Epub 2011 Aug 24.

DOI:10.1007/s00404-011-2035-2
PMID:21863311
Abstract

OBJECTIVE

To evaluate the role of endometrial/uterine corporeal volume ratio for the prediction of endometrial malignancy in cases of postmenopausal bleeding.

METHODS

Endometrial volumes and uterine body volumes excluding cervices measured by VOCAL (virtual organ computer-aided analysis) were estimated in 160 women with postmenopausal bleeding. Endometrial/uterine corporeal volume ratios were calculated for all. Endometrial biopsies and histopathological results were obtained for all. One hundred normal postmenopausal women were included as controls.

RESULTS

Histopathological results of the 160 women with postmenopausal bleeding revealed 53 atypia, 27 endometrial cancer and 80 benign conditions. An endometrial/uterine volume (EV/UCV) ratio of a cutoff value >0.017 was predictive of malignancy. Endometrial/uterine volume ratio was more sensitive than endometrial volume and endometrial thickness for prediction of endometrial cancer.

CONCLUSION

An endometrial/uterine volume ratio (EV/UCV) >0.017 is predictive of malignancy. (EV/UCV) was more accurate in the prediction of malignancy than endometrial thickness and endometrial volume.

摘要

目的

评估绝经后出血患者子宫内膜/子宫体体积比预测子宫内膜恶性肿瘤的作用。

方法

通过 VOCAL(虚拟器官计算机辅助分析)对 160 例绝经后出血患者的子宫内膜体积和不包括宫颈的子宫体体积进行评估。计算所有患者的子宫内膜/子宫体体积比。对所有患者进行子宫内膜活检和组织病理学检查。同时纳入 100 例正常绝经后妇女作为对照组。

结果

160 例绝经后出血患者的组织病理学检查结果显示 53 例不典型增生、27 例子宫内膜癌和 80 例良性病变。子宫内膜/子宫体体积比(EV/UCV)的截断值>0.017 可预测恶性肿瘤。与子宫内膜厚度和子宫内膜体积相比,EV/UCV 对子宫内膜癌的预测更敏感。

结论

子宫内膜/子宫体体积比(EV/UCV)>0.017 可预测恶性肿瘤。EV/UCV 比子宫内膜厚度和子宫内膜体积更准确地预测恶性肿瘤。

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Arch Gynecol Obstet. 2012 Mar;285(3):831-8. doi: 10.1007/s00404-011-2035-2. Epub 2011 Aug 24.
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