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[肾细胞癌的手术治疗]

[Operative treatment of renal cell carcinoma].

作者信息

Heidenreich A

机构信息

Klinik und Poliklinik für Urologie, Universitätsklinikum Aachen, Pauwelsstrasse 30, Aachen, Germany.

出版信息

Urologe A. 2011 Sep;50 Suppl 1:208-15. doi: 10.1007/s00120-011-2670-z.

DOI:10.1007/s00120-011-2670-z
PMID:21863410
Abstract

Renal cell carcinoma represents the fifth most frequent malignant tumor in humans. At the time of diagnosis, 20% of the patients already manifest metastases. A further 20-30% of the patients develop systemic metastases in the postoperative course. Despite continued advances in pharmacological treatment options, cancer surgery tailored to the individual tumor findings constitutes the only curative treatment option.

摘要

肾细胞癌是人类中第五大常见恶性肿瘤。在确诊时，20%的患者已出现转移。另外20%-30%的患者在术后病程中会发生全身转移。尽管药物治疗选择不断进步，但根据个体肿瘤情况定制的癌症手术仍是唯一的治愈性治疗选择。

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引用本文的文献

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[Laparoscopic partial nephrectomy for renal tumors. Time for a new standard?].[腹腔镜肾部分切除术治疗肾肿瘤。是时候采用新标准了吗？]
Urologe A. 2015 Jun;54(6):826-31. doi: 10.1007/s00120-014-3656-4.

本文引用的文献

1
Renal cell carcinoma in octogenarians: nephron sparing surgery should remain the standard of care.80 岁以上老年人肾细胞癌：保留肾单位手术应作为标准治疗方法。
J Urol. 2011 Feb;185(2):415-20. doi: 10.1016/j.juro.2010.09.071. Epub 2010 Dec 17.
2
Contemporary management of renal tumors with venous tumor thrombus.当代肾肿瘤伴静脉瘤栓的治疗方法。
J Urol. 2010 Sep;184(3):833-41; quiz 1235. doi: 10.1016/j.juro.2010.04.071.
3
Nephron-sparing surgery is equally effective to radical nephrectomy for T1BN0M0 renal cell carcinoma: a population-based assessment.
保肾手术与根治性肾切除术治疗 T1BN0M0 期肾细胞癌同样有效：基于人群的评估。
Urology. 2010 Feb;75(2):271-5. doi: 10.1016/j.urology.2009.04.098. Epub 2009 Dec 4.
4
Surgical resection of renal cell carcinoma after targeted therapy.靶向治疗后肾细胞癌的手术切除
J Urol. 2009 Sep;182(3):881-6. doi: 10.1016/j.juro.2009.05.014. Epub 2009 Jul 17.
5
Neoadjuvant (presurgical) therapy for renal cell carcinoma: a new treatment paradigm for locally advanced and metastatic disease.肾细胞癌的新辅助（术前）治疗：局部晚期和转移性疾病的新治疗模式。
Cancer. 2009 May 15;115(10 Suppl):2355-60. doi: 10.1002/cncr.24240.
6
Radical nephrectomy with and without lymph-node dissection: final results of European Organization for Research and Treatment of Cancer (EORTC) randomized phase 3 trial 30881.根治性肾切除术伴或不伴淋巴结清扫术：欧洲癌症研究与治疗组织（EORTC）随机 3 期试验 30881 的最终结果。
Eur Urol. 2009 Jan;55(1):28-34. doi: 10.1016/j.eururo.2008.09.052. Epub 2008 Oct 1.
7
Treatment with sunitinib enabled complete resection of massive lymphadenopathy not previously amenable to excision in a patient with renal cell carcinoma.舒尼替尼治疗使一名肾癌患者先前无法切除的巨大淋巴结病完全切除成为可能。
Eur Urol. 2009 Jan;55(1):237-9; quiz 239. doi: 10.1016/j.eururo.2008.09.006. Epub 2008 Sep 17.
8
Preoperative tyrosine kinase inhibition as an adjunct to debulking nephrectomy.术前酪氨酸激酶抑制作为减瘤性肾切除术的辅助治疗
Urology. 2008 Oct;72(4):864-8. doi: 10.1016/j.urology.2008.01.088. Epub 2008 Aug 5.
9
Renal and cardiovascular morbidity after partial or radical nephrectomy.部分或根治性肾切除术后的肾脏和心血管发病率
Cancer. 2008 Feb 1;112(3):511-20. doi: 10.1002/cncr.23218.
10
Neoadjuvant sutent induction therapy may effectively down-stage renal cell carcinoma atrial thrombi.新辅助舒尼替尼诱导治疗可能有效降低肾细胞癌伴心房血栓的分期。
Eur Urol. 2008 Apr;53(4):845-8. doi: 10.1016/j.eururo.2007.11.006. Epub 2007 Nov 20.