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腹型癫痫:一种罕见的非惊厥性癫痫持续状态。

Abdominal epilepsy: an uncommon of non-convulsive status epilepticus.

作者信息

Tiamkao Somsak, Pratipanawatr Thongchai, Jitpimolmard Suthipun

机构信息

Division of Neurology, Deparment of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

出版信息

J Med Assoc Thai. 2011 Aug;94(8):998-1001.

Abstract

OBJECTIVE

To recognize abdominal epilepsy in adults.

MATERIAL AND METHOD

Case report.

RESULTS

Case 1: A 21-year-old woman with DM type I presented with a 2-month history involving four episodes of severe abdominal pain and vomiting, each of which lasted four to five days. She had a recurrence every two weeks. The EEG revealed 'spike and wave ' and she was started an intravenous phenytoin that resolved the symptoms. Case 2: A 20-year-old woman with DM type I was admitted with a 2-month history of recurring severe left upper quadrant pain associated with occasional nausea but no vomiting. She experienced two more episodes of generalized tonic-clonic seizures and was treated with 300 mg phenytoin given orally The abdominal pains gradually subsided and she was symptom-free within two days. An EEG showed frequent sharp waves. She was treated with 10 mg intravenous diazepam and her symptoms and sharp waves disappeared within two minutes. Case 3: A 46-year-old man with DM type I was admitted with a four-month history of recurring severe epigastric pain and vomiting. His physical examination, laboratory tests, and extensive investigation for a primary GI disorder revealed nothing unusual. The EEG revealed spike and wave and he was treated with intravenous AED (phenytoin) loading after which the symptoms disappeared.

CONCLUSION

Physicians should consider abdominal epilepsy in diabetics with recurrent, intractable abdominal pain in whom extensive investigations for primary gastrointestinal (GI) disorders are unremarkable.

摘要

目的

认识成人腹部癫痫。

材料与方法

病例报告。

结果

病例1:一名1型糖尿病21岁女性,有2个月病史,发作4次严重腹痛和呕吐,每次持续4至5天。每两周复发一次。脑电图显示“棘波和慢波”,开始静脉注射苯妥英钠后症状缓解。病例2:一名1型糖尿病20岁女性入院,有2个月复发性严重左上腹疼痛病史,伴有偶尔恶心但无呕吐。她又经历了2次全身强直阵挛发作,口服300毫克苯妥英钠治疗。腹痛逐渐缓解,两天内症状消失。脑电图显示频繁尖波。静脉注射10毫克地西泮治疗,两分钟内症状和尖波消失。病例3:一名1型糖尿病46岁男性入院,有4个月复发性严重上腹部疼痛和呕吐病史。他的体格检查、实验室检查以及对原发性胃肠道疾病的广泛检查均未发现异常。脑电图显示棘波和慢波,静脉注射抗癫痫药物(苯妥英钠)负荷量治疗后症状消失。

结论

对于患有复发性、顽固性腹痛且对原发性胃肠道疾病进行广泛检查无明显异常的糖尿病患者,医生应考虑腹部癫痫。

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