Mazo E B, Akopian A S, Koriakin M V, Kuznetsova B A
Urol Nefrol (Mosk). 1990 Jan-Feb(1):22-7.
Based on the analysis of a RX-ray study and a selective blood test for the activity of the plasma renin, aldesterone, hydrocortisone and adrenocorticotropic hormone (ACTH) in 57 patients with arterial hypertension--14 persons without renal failure, 14 ones regularly treated by hemodialysis, 29 patients with left orthostatic varicocele--the authors demonstrated the impact of the renal arterio- and phlebography on the hormone levels studied. Arteriography resulted in an increase in the absolute value of the renal vein renin mean 2.1-fold, aldosterone, 3.3-fold and hydrocortisone, 1.7-fold. A 2.2-fold increase in the renin activity and a 2.6-fold increase in the levels of aldosterone and hydrocortisone noted in all the patients were the result of retrograde renal phlebography. No correlations were established between the changes in hormone levels and the central mechanism of the secretion regulation (ACTH). Radiopaque investigations of the patients with arterial hypertension gave 22 per cent of false positive results with regard to the site of renin secretion and 18 per cent of those with regard to the participation of the studied kidney in renin secretion. The authors supposed a possible regulation of adrenal mineralocorticoid performance by a retrograde blood flow appeared through the adrenal central veins that was induced by phlebography--related elevation of blood pressure in the renal vein.
基于对57例高血压患者进行的X线研究以及血浆肾素、醛固酮、氢化可的松和促肾上腺皮质激素（ACTH）活性的选择性血液检测分析——其中14例无肾衰竭，14例接受定期血液透析治疗，29例患有左立位静脉曲张——作者证明了肾动静脉造影对所研究激素水平的影响。动脉造影导致肾静脉肾素绝对值平均增加2.1倍，醛固酮增加3.3倍，氢化可的松增加1.7倍。所有患者肾素活性增加2.2倍，醛固酮和氢化可的松水平增加2.6倍是逆行肾静脉造影的结果。激素水平变化与分泌调节的中枢机制（ACTH）之间未建立相关性。对高血压患者进行的不透X线检查在肾素分泌部位方面产生了22%的假阳性结果，在所研究肾脏参与肾素分泌方面产生了18%的假阳性结果。作者推测，静脉造影相关的肾静脉血压升高所引发的逆行血流可能通过肾上腺中央静脉对肾上腺盐皮质激素功能进行调节。
