Togawa Akihisa, Hotomi Muneki, Tamura Shinji, Yamanaka Noboru
Department of Otolaryngology, Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.
Adv Otorhinolaryngol. 2011;72:139-41. doi: 10.1159/000324771. Epub 2011 Aug 18.
The aim of this study was to evaluate clinical outcomes of acute pharyngo-tonsillitis by a scoring system and the impact of causative pathogens.
The patients with acute pharyngotonsillitis were evaluated for causative pathogens and her clinical symptoms and pharyngotonsillar finding by a clinical scoring system were assessed.
Streptocococcus pyogenes were identified at 13.6%. Thirty-one viruses were also identified by PCR. The numbers of total white blood cells and the levels of C-reactive protein showed a significant positive correlation with clinical scores (p<0.001) and were significantly higher in cases with S. pyogenes. The clinical scores rapidly improved after the antimicrobial treatments in moderate cases and severe cases.
A clinical scoring system represents the severity of acute pharyngotonsillitis and is useful for evaluating clinical course of the illness.
本研究旨在通过一种评分系统评估急性咽扁桃体炎的临床结局以及致病病原体的影响。
对急性咽扁桃体炎患者进行致病病原体评估,并通过临床评分系统评估其临床症状和咽扁桃体检查结果。
化脓性链球菌的检出率为13.6%。通过聚合酶链反应还鉴定出31种病毒。白细胞总数和C反应蛋白水平与临床评分呈显著正相关(p<0.001),在化脓性链球菌感染的病例中显著更高。中度和重度病例在接受抗菌治疗后临床评分迅速改善。
临床评分系统可反映急性咽扁桃体炎的严重程度,有助于评估疾病的临床进程。