Patterson R, Roberts M, Grammer L C
Department of Medicine, Northwestern University Medical School, Chicago, Illinois.
Ann Allergy. 1990 May;64(5):459-62.
We reevaluated IgE-mediated insulin allergy using sera obtained 16 to 21 years ago and, 1 and 5 years ago. All antibodies had specificity for human and bovine insulin. We reevaluated Prausnitz-Kustner reactivity after 15 years and the IgE antibody and cutaneous reactivity appeared unchanged. IgE-mediated insulin allergy appears to be declining.
我们使用16至21年前以及1年前和5年前获取的血清对IgE介导的胰岛素过敏进行了重新评估。所有抗体对人胰岛素和牛胰岛素均具有特异性。15年后我们重新评估了普劳斯尼茨-屈斯特纳反应性,IgE抗体和皮肤反应性似乎未发生变化。IgE介导的胰岛素过敏似乎正在减少。