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结节性硬化症伴发胎儿及新生儿心脏肿瘤。

Tuberous sclerosis presenting with fetal and neonatal cardiac tumours.

作者信息

Wallace G, Smith H C, Watson G H, Rimmer S, D'Souza S W

机构信息

Royal Manchester Children's Hospital, Pendlebury.

出版信息

Arch Dis Child. 1990 Apr;65(4 Spec No):377-9. doi: 10.1136/adc.65.4_spec_no.377.

DOI:10.1136/adc.65.4_spec_no.377
PMID:2186708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1590155/
Abstract

Cardiac tumours were identified on ultrasonography in fetal or early postnatal life in five infants. Tuberous sclerosis was subsequently diagnosed in all five. Only one infant required operation. Regression of the tumour occurred in three. No infant had hypomelanotic macules at birth, and they took up to two years to appear.

摘要

五名婴儿在胎儿期或出生后早期通过超声检查发现心脏肿瘤。随后这五名婴儿均被诊断为结节性硬化症。只有一名婴儿需要手术。三名婴儿的肿瘤发生了消退。没有婴儿在出生时就有色素减退斑,这些斑最多需要两年时间才会出现。

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本文引用的文献

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Primary cardiac tumors in children.儿童原发性心脏肿瘤
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Cardiac rhabdomyomata as a marker for the antenatal detection of tuberous sclerosis.心脏横纹肌瘤作为产前检测结节性硬化症的标志物。
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Ultrasonic patterns of a cardiac rhabdomyoma detected in utero.子宫内检测到的心脏横纹肌瘤的超声图像
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The heart and tuberous sclerosis. An echocardiographic and electrocardiographic study.心脏与结节性硬化症。一项超声心动图和心电图研究。
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Cardiac rhabdomyomas in a newborn baby. Early diagnosis and treatment.新生儿心脏横纹肌瘤。早期诊断与治疗。
Acta Paediatr Scand. 1985 Sep;74(5):824-7. doi: 10.1111/j.1651-2227.1985.tb10043.x.
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Echocardiographic incidence of cardiac rhabdomyoma in tuberous sclerosis.
Am J Cardiol. 1985 May 1;55(11):1379-82. doi: 10.1016/0002-9149(85)90508-9.
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The late appearance of hypopigmented maculae in tuberous sclerosis.
Am J Dis Child. 1985 Apr;139(4):408-9. doi: 10.1001/archpedi.1985.02140060090039.
9
Tuberous sclerosis: a clinicoradiological evaluation of 110 cases with particular reference to atypical presentation.结节性硬化症:110例临床放射学评估,特别提及非典型表现
Neuroradiology. 1986;28(1):38-46. doi: 10.1007/BF00341764.
10
Prenatal diagnosis of tuberous sclerosis: the use of fetal echocardiography.结节性硬化症的产前诊断:胎儿超声心动图的应用
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