Department of Pharmacy Practice, Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Australia.
Int Breastfeed J. 2011 Aug 26;6:11. doi: 10.1186/1746-4358-6-11.
Many breastfeeding women require and regularly take medicines, especially those available over-the-counter, and the safe use of these is dependent on the advice provided by health professionals such as general practitioners and pharmacists. The primary aim of this review therefore, was to investigate the literature relating to health professionals' and women's knowledge, attitudes and practices towards medication use and safety in breastfeeding. The limited literature that was uncovered identified that general practitioners and pharmacists have poor knowledge, but positive attitudes, and variable practices that are mostly guided by personal experience. They tend to make decisions about the use of a medicine whilst breastfeeding based on the potential 'risk' that it poses to the infant in terms of possible adverse reactions, rather than its 'compatibility' with breast milk. The decision-making process between health professionals and women is usually not a negotiated process, and women are often asked to stop breastfeeding whilst taking a medicine. Women, in turn, are left dissatisfied with the advice received, many choosing not to initiate therapy or not to continue breastfeeding. Some directions for future research have been suggested to address the issues identified in this critical area. This review is important from a societal perspective because many breastfeeding women require and regularly take medications, especially those available without prescription, and the safe use of these is dependent on the advice provided by health professionals, which is ultimately influenced by their knowledge, attitudes and practices. However, there is an absence of high quality evidence from randomised controlled trials on the safety of medications taken during breastfeeding, which naturally would hinder health professionals from appropriately advising women. It is equally important to know about women's experiences of advice received from health professionals, and whether there is consistency between recommendations made across resources on medication safety in breastfeeding, in order to gain a full understanding of the issues prevalent in this area of practice.
许多哺乳期妇女需要并经常服用药物,尤其是那些非处方药物,而这些药物的安全使用取决于医生和药剂师等卫生专业人员提供的建议。因此,本次综述的主要目的是调查与卫生专业人员和妇女对哺乳期用药安全的知识、态度和实践相关的文献。所发现的有限文献表明,医生和药剂师的知识有限,但态度积极,且实践情况各异,主要取决于个人经验。他们在决定是否在哺乳期使用药物时,通常不是基于药物对婴儿可能产生的不良反应的“风险”,而是基于其与母乳的“相容性”。卫生专业人员和妇女之间的决策过程通常不是协商过程,妇女经常被要求在服用药物时停止母乳喂养。反过来,妇女对所收到的建议感到不满,许多人选择不开始治疗或不继续母乳喂养。为了解决这一关键领域存在的问题,已经提出了一些未来研究的方向。从社会角度来看,本次综述很重要,因为许多哺乳期妇女需要并经常服用药物,尤其是那些非处方药物,而这些药物的安全使用取决于医生和药剂师等卫生专业人员提供的建议,而这最终受到他们的知识、态度和实践的影响。然而,由于哺乳期服用药物的安全性缺乏高质量的随机对照试验证据,卫生专业人员自然难以恰当地为妇女提供建议。了解妇女从卫生专业人员那里获得的建议的经验,以及在哺乳期用药安全方面的资源建议之间是否存在一致性,同样重要,以便全面了解该实践领域普遍存在的问题。