头颈部黏膜相关淋巴组织淋巴瘤的临床研究
Clinical study of mucosa-associated lymphoid tissue lymphomas of the head and neck.
作者信息
Hosokawa S, Okamura J, Takizawa Y, Takahashi G, Hosokawa K, Mineta H
机构信息
Department of Otolaryngology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
出版信息
J Laryngol Otol. 2012 Mar;126(3):271-5. doi: 10.1017/S0022215111002192. Epub 2011 Aug 26.
BACKGROUND
Limited information is available on mucosa-associated lymphoid tissue lymphomas arising in the head and neck.
METHOD
A retrospective analysis was conducted of 20 patients who were histologically diagnosed with mucosa-associated lymphoid tissue lymphoma and treated at our institution between January 1990 and December 2009.
RESULTS
Treatment consisted of surgical resection alone in two patients (10 per cent), surgical resection with consecutive radiotherapy in one (5 per cent), and radiotherapy alone in eight (40 per cent). Three patients (15 per cent) were treated with systemic chemotherapy, and three (15 per cent) received chemoradiotherapy. Three patients (15 per cent) were informed of the diagnosis but not treated for their condition.
CONCLUSION
All of the 20 patients were still alive after a mean follow-up period of 50.8 months. Local treatment for mucosa-associated lymphoid tissue lymphoma of the head and neck should be the first choice in early-stage disease. However, prolonged follow up is important to determine these patients' long-term response to treatment.
背景
关于头颈部黏膜相关淋巴组织淋巴瘤的信息有限。
方法
对1990年1月至2009年12月间在本机构接受治疗且经组织学诊断为黏膜相关淋巴组织淋巴瘤的20例患者进行回顾性分析。
结果
2例患者（10%）仅接受手术切除治疗，1例（5%）接受手术切除并序贯放疗，8例（40%）仅接受放疗。3例患者（15%）接受全身化疗，3例（15%）接受放化疗。3例患者（15%）被告知诊断结果但未接受治疗。
结论
20例患者在平均随访50.8个月后均存活。头颈部黏膜相关淋巴组织淋巴瘤的局部治疗应作为早期疾病的首选。然而，延长随访对于确定这些患者对治疗的长期反应很重要。
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