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RT-PCR and real-time PCR analysis of E2A-PBX1, TEL-AML1, mBCR-ABL and MLL-AF4 fusion gene transcripts in de novo B-lineage acute lymphoblastic leukaemia patients in south India.

作者信息

Sudhakar Natarajan, Rajalekshmy Kamalalayam Raghavan, Rajkumar Thangarajan, Nancy Karunakaran Nirmala

机构信息

Department of Molecular Oncology, Cancer Institute, WIA 38, Sardar Patel Road, Chennai 600 036, India.

出版信息

J Genet. 2011 Aug;90(2):349-53. doi: 10.1007/s12041-011-0080-z.

DOI:10.1007/s12041-011-0080-z
PMID:21869488
Abstract
摘要

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The application of conventional cytogenetics, FISH, and RT-PCR to detect genetic changes in 70 children with ALL.应用传统细胞遗传学、荧光原位杂交技术（FISH）和逆转录聚合酶链反应（RT-PCR）检测70例急性淋巴细胞白血病患儿的基因变化。
Ann Hematol. 2008 Dec;87(12):991-1002. doi: 10.1007/s00277-008-0540-6. Epub 2008 Jul 17.
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Turk J Haematol. 2022 Feb 23;39(1):1-12. doi: 10.4274/tjh.galenos.2021.2021.0326. Epub 2021 Oct 7.
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Molecular Detection of Fusion Oncogenes in Zambian Patients with Acute Lymphoblastic Leukemia.赞比亚急性淋巴细胞白血病患者融合致癌基因的分子检测
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本文引用的文献

1
Multiplex reverse transcription-polymerase chain reaction as diagnostic molecular screening of 4 common fusion chimeric genes in Taiwanese children with acute lymphoblastic leukemia.多重逆转录-聚合酶链反应用于台湾急性淋巴细胞白血病儿童4种常见融合嵌合基因的诊断性分子筛查。
J Pediatr Hematol Oncol. 2010 Nov;32(8):e323-30. doi: 10.1097/MPH.0b013e3181ed1655.
2
The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers.机械因素在促进淋巴和其他癌症中发现的染色体易位中的作用。
Adv Immunol. 2010;106:93-133. doi: 10.1016/S0065-2776(10)06004-9.
3
Frequencies of ETV6-RUNX1 fusion and hyperdiploidy in pediatric acute lymphoblastic leukemia are lower in far east than west.
Pattern of chromosome involvement in childhood hyperdiploid pre-B-cell acute lymhoblastic leukemia cases from India.
印度儿童高倍体前B细胞急性淋巴细胞白血病病例中的染色体受累模式。
Indian J Hum Genet. 2014 Jan;20(1):32-6. doi: 10.4103/0971-6866.132751.
在远东部，儿童急性淋巴细胞白血病中 ETV6-RUNX1 融合和超二倍体的频率低于西部。
Pediatr Blood Cancer. 2010 Sep;55(3):430-3. doi: 10.1002/pbc.22628.
4
Simple multiplex RT-PCR for identifying common fusion transcripts in childhood acute leukemia.用于鉴定儿童急性白血病常见融合转录本的简单多重逆转录聚合酶链反应
Int J Lab Hematol. 2008 Aug;30(4):286-91. doi: 10.1111/j.1751-553X.2007.00954.x.
5
BCR-ABL, ETV6-RUNX1 and E2A-PBX1: prevalence of the most common acute lymphoblastic leukemia fusion genes in Mexican patients.BCR-ABL、ETV6-RUNX1和E2A-PBX1：墨西哥患者中最常见的急性淋巴细胞白血病融合基因的患病率
Leuk Res. 2008 Oct;32(10):1518-22. doi: 10.1016/j.leukres.2008.03.021. Epub 2008 May 5.
6
The t(12:21) is underrepresented in childhood B-lineage acute lymphoblastic leukemia in Kerala, Southern India.在印度南部喀拉拉邦的儿童B系急性淋巴细胞白血病中，t(12;21)的比例较低。
Haematologica. 2005 Mar;90(3):414-6.
7
Paucity of TEL-AML 1 translocation, by multiplex RT-PCR, in B-lineage acute lymphoblastic leukemia (ALL) in Indian patients.
Am J Hematol. 2004 May;76(1):80-2. doi: 10.1002/ajh.20000.
8
Origins of chromosome translocations in childhood leukaemia.儿童白血病中染色体易位的起源
Nat Rev Cancer. 2003 Sep;3(9):639-49. doi: 10.1038/nrc1164.
9
Preclinical validation of a monochrome real-time multiplex assay for translocations in childhood acute lymphoblastic leukemia.用于儿童急性淋巴细胞白血病易位检测的单色实时多重分析方法的临床前验证
Clin Cancer Res. 2002 Dec;8(12):3832-40.
10
TEL/AML1-positive pediatric leukemia: prognostic significance and therapeutic approaches.TEL/AML1阳性小儿白血病：预后意义及治疗方法
Curr Opin Hematol. 2002 Jul;9(4):345-52. doi: 10.1097/00062752-200207000-00013.