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[Nerve growth factor as a therapeutic agent: transplantation of brain tissue as a possible treatment of neurodegenerative disorders].

作者信息

Ebendal T, Olson L, Persson H

机构信息

Institutionen för miljömedicinsk utvecklingsbiologi, Uppsala biomedicinska centrum, Uppsala universitet.

出版信息

Lakartidningen. 1990 May 16;87(20):1773-4, 1777-80.

PMID:2187136
Abstract

An account of experiments focused on the treatment of neurodegenerative disease by means of cell grafts, in which genetically modified cells that release abundant nerve growth factor are described, and their transplantation to the rat brain reported. The cells can survive in the rat brain and exert potent effects on cholinergic neurons both in the host cortex, basal forebrain and striatum, and in tissue grafts.

摘要

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