Division of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
Cytokine. 2012 Apr;58(1):112-7. doi: 10.1016/j.cyto.2011.07.430. Epub 2011 Aug 26.
Histoplasma capsulatum is a prevalent fungal pathogen in the United States, infecting approximately 500,000 individuals each year. Host protection requires an intact cell-mediated immune response. In this review, we will discuss how cytokines and chemokines influence protective immunity in H. capsulatum infection.
荚膜组织胞浆菌是美国流行的真菌病原体,每年感染约 50 万人。宿主保护需要完整的细胞介导免疫反应。在这篇综述中,我们将讨论细胞因子和趋化因子如何影响荚膜组织胞浆菌感染中的保护性免疫。