中枢神经系统孤立性纤维性肿瘤：1996年至2010年所有报告病例的临床、影像学及病理表现综述

The central nervous system solitary fibrous tumor: a review of clinical, imaging and pathologic findings among all reported cases from 1996 to 2010.

作者信息

Fargen Kyle M, Opalach Katherine J, Wakefield Dara, Jacob R Patrick, Yachnis Anthony T, Lister J Richard

机构信息

Department of Neurosurgery, University of Florida College of Medicine, Gainesville, FL, USA.

出版信息

Clin Neurol Neurosurg. 2011 Nov;113(9):703-10. doi: 10.1016/j.clineuro.2011.07.024. Epub 2011 Aug 26.

DOI:10.1016/j.clineuro.2011.07.024

PMID:21872387

Abstract

OBJECTIVE

Central nervous system (CNS) solitary fibrous tumor (SFT) is a rare lesion first identified as a unique entity in 1996. We describe two cases treated at the University of Florida followed by a review of all reported cases of CNS SFT between 1996 and 2010.

METHODS

A review of the literature was performed to identify all reported cases of CNS SFT.

RESULTS

189 cases (including the two presented herein) were discovered, of which 46 were spinal and 143 were intracranial. Demographic, imaging, and pathologic findings are presented. Roughly 6% of reported lesions are malignant. Subtotal resection (STR) was associated with a 16-fold increased odds of recurrence (OR 15.9, 95% CI 5.5-46.1), although mean follow-up was shorter in those cases of GTR without recurrence.

CONCLUSION

CNS SFT is a rare lesion. Six percent of lesions are malignant. GTR is superior to STR although the degree of superiority is not clear.

摘要

目的

中枢神经系统（CNS）孤立性纤维性肿瘤（SFT）是一种罕见病变，于1996年首次被确认为一种独特的实体。我们描述了在佛罗里达大学治疗的两例病例，并对1996年至2010年间所有报道的CNS SFT病例进行了回顾。

方法

对文献进行回顾，以确定所有报道的CNS SFT病例。

结果

共发现189例（包括本文所呈现的两例），其中46例为脊髓肿瘤，143例为颅内肿瘤。呈现了人口统计学、影像学和病理学结果。大约6%的报道病变为恶性。次全切除（STR）与复发几率增加16倍相关（比值比15.9，95%置信区间5.5 - 46.1），尽管在那些未复发的全切（GTR）病例中平均随访时间较短。