Başkurt Ozan, Şeker Selim, Avci Idris
Neurosurgery, İstinye University Faculty of Medicine, Istanbul, TUR.
Neurosurgery, İstinye University Liv Hospital Bahcesehir, Istanbul, TUR.
Cureus. 2024 Dec 17;16(12):e75850. doi: 10.7759/cureus.75850. eCollection 2024 Dec.
Intracranial solitary fibrous tumors (SFTs) and hemangiopericytomas (HPCs) are rare, aggressive tumors typically found along the dural sinuses. Despite their aggressive nature, complete surgical resection remains the most significant factor in reducing recurrence and improving survival. Here, we present the case of a 32-year-old male patient who presented with a new-onset headache and vertigo. Magnetic resonance imaging revealed a 50×37 mm left occipital mass originating from the falx and extending into the tentorium, with heterogeneous enhancement and compression/invasion of the left transverse sinus. Total resection was accomplished using microsurgical techniques, and histopathological analysis confirmed SFT/HPC, classified as WHO Grade II. Given the complete resection, including the venous sinus involvement, adjuvant radiotherapy was deemed unnecessary by the multidisciplinary committee. At the latest follow-up, five years post surgery, the patient showed no residual tumor or recurrence, with a reported overall well-being. Early detection and aggressive management through total resection can significantly improve survival and prognosis in patients with SFTs/HPCs.
颅内孤立性纤维瘤（SFTs）和血管外皮细胞瘤（HPCs）是罕见的侵袭性肿瘤，通常位于硬脑膜窦附近。尽管它们具有侵袭性，但完整的手术切除仍然是降低复发率和提高生存率的最重要因素。在此，我们报告一例32岁男性患者，他出现新发头痛和眩晕。磁共振成像显示一个50×37毫米的左枕叶肿块，起源于大脑镰并延伸至小脑幕，有不均匀强化，且压迫/侵犯左横窦。采用显微外科技术完成了全切，组织病理学分析证实为SFT/HPC，分类为世界卫生组织二级。鉴于包括静脉窦受累在内的全切情况，多学科委员会认为无需辅助放疗。在术后五年的最新随访中，患者无残留肿瘤或复发，报告总体状况良好。通过全切进行早期检测和积极治疗可显著改善SFTs/HPCs患者的生存率和预后。
