Chair of Maxillo-Facial Surgery (Chairman: Prof. L. Califano), School of Medicine, University of Naples Federico II, Via S. Pansini 5, 80100 Napoli, Italy.
J Craniomaxillofac Surg. 2012 Jul;40(5):421-6. doi: 10.1016/j.jcms.2011.07.015. Epub 2011 Aug 27.
A long-term survey on the healing potential of large-sized parasymphyseal osseous defects.
Ten patients, subjected to 14 bilateral and 3 unilateral parasymphyseal bone harvesting for alveolar ridge augmentation, were selected for the retrospective chart review. CT scans were performed immediately before bone grafting, before implant insertion, and then once annually for 6 years, and the volumes of the bone defects at the buccal aspect in the healing process were measured using a software program. Volumes from the yearly measurements were then compared statistically.
Volumes of both the intrasurgical defects, 0.77 (0.20) cc and of those in the one-year group, 0.60 (0.26) cc were statistically different from volumes of all the other time intervals (from 24 to 72 months) with all p-values less than 0.002 and 0.004, respectively. The healing of osseous defects in the long-term radiographic survey (6 years) resulted in bony infill of 63%.
For parasymphyseal defects of 0.7 cc, a maximum possible healing of two-thirds can be expected; a re-harvesting procedure could be performed 24 months after early surgery, due to both the formation of a new buccal cortical plate and the achievement of a steady state of osseous remodelling.
对大型正中联合骨缺损愈合潜能的长期研究。
选择了 10 名患者，他们接受了 14 次双侧和 3 次单侧正中联合骨采集，用于牙槽嵴增高。对这些患者进行回顾性图表审查。在骨移植前、植入前和随后的 6 年内每年进行一次 CT 扫描，并使用软件程序测量愈合过程中颊侧骨缺损的体积。然后对每年的测量值进行统计学比较。
术中缺损的体积（0.77[0.20]cc）和一年组的体积（0.60[0.26]cc）与所有其他时间间隔（24 至 72 个月）的体积均有统计学差异，所有 p 值均小于 0.002 和 0.004。在长期影像学研究（6 年）中，骨缺损的愈合导致了 63%的骨填充。
对于 0.7cc 的正中联合缺损，可以预期最大可能的愈合程度为三分之二；由于新的颊侧皮质板的形成和骨重塑的稳定状态，可以在早期手术后 24 个月进行再次采集。
